Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia

Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia

Abstract Some individuals, even when heavily exposed to an infectious tuberculosis patient, do not develop a specific T-cell response as measured by interferon-gamma release assay (IGRA). This could be explained by an IFN-γ-independent adaptive immune response, or an effective innate host response c...

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Main Authors: Todia P. Setiabudiawan, Lika Apriani, Ayesha J. Verrall, Fitria Utami, Marion Schneider, Agnes R. Indrati, Pauline P. Halim, Paulina Kaplonek, Hadar Malca, Jessica Shih-Lu Lee, Simone J. C. F. M. Moorlag, L. Charlotte J. de Bree, Vera P. Mourits, Leo A. B. Joosten, Mihai G. Netea, Bachti Alisjahbana, Ryan P. McNamara, Galit Alter, Arjan van Laarhoven, James E. Ussher, Katrina Sharples, Valerie A. C. M. Koeken, Philip C. Hill, Reinout van Crevel
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55501-6
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