Combination effects of Pistachio hull and carfilzomib on NF-κB p65, MDR1, MRP1, and Caspase3 gene expression in breast cancer cell line

Combination effects of Pistachio hull and carfilzomib on NF-κB p65, MDR1, MRP1, and Caspase3 gene expression in breast cancer cell line

Abstract Objective This study aimed to investigate the synergistic effects of the chemotherapy drug Carfilzomib (CFZ) and Pistachio hull extract on the SK-BR3 breast cancer cell line. Methods In this experimental study, we evaluated the effect of Pistachio hull extract and CFZ as standalone treatmen...

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Bibliographic Details
Main Authors: Zahra Mirzaei, Sadegh Zarei, Ahmadreza Sayadi, Reza Hosseiniara, Mojgan Noroozi Karimabad, Mehdi Mahmoodi
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Pistachio hull extract
Carfilzomib
Combination therapy
Breast cancer
Online Access:https://doi.org/10.1186/s12906-024-04716-7
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