Myocardial Gene Expression of T-bet, GATA-3, Ror-γt, FoxP3, and Hallmark Cytokines in Chronic Chagas Disease Cardiomyopathy: An Essentially Unopposed TH1-Type Response
Background. Chronic Chagas disease cardiomyopathy (CCC), a late consequence of Trypanosoma cruzi infection, is an inflammatory cardiomyopathy with prognosis worse than those of noninflammatory etiology (NIC). Although the T cell-rich myocarditis is known to play a pathogenetic role, the relative co...
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Main Authors: | Luciana Gabriel Nogueira, Ronaldo Honorato Barros Santos, Alfredo Inácio Fiorelli, Eliane Conti Mairena, Luiz Alberto Benvenuti, Edimar Alcides Bocchi, Noedir Antonio Stolf, Jorge Kalil, Edecio Cunha-Neto |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2014/914326 |
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