Transcriptome and Physiological Analyses of Resistant and Susceptible Pepper (<i>Capsicum annuum</i>) to <i>Verticillium dahliae</i> Inoculum

Pepper (<i>Capsicum annuum</i>) is a globally important vegetable, and Verticillium wilt is an important disease affecting peppers and is caused by <i>Verticillium dahliae</i>, which can severely reduce yields. However, the molecular mechanisms underlying the responses of pep...

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Main Authors: Xinmin Huang, Liming He, Huimin Tan, Jiayi Liu, Qiucheng Qiu, Qidi Sun, Lejun Ouyang, Hanbing Han, Qinqin He
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Horticulturae
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Online Access:https://www.mdpi.com/2311-7524/10/11/1160
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author Xinmin Huang
Liming He
Huimin Tan
Jiayi Liu
Qiucheng Qiu
Qidi Sun
Lejun Ouyang
Hanbing Han
Qinqin He
author_facet Xinmin Huang
Liming He
Huimin Tan
Jiayi Liu
Qiucheng Qiu
Qidi Sun
Lejun Ouyang
Hanbing Han
Qinqin He
author_sort Xinmin Huang
collection DOAJ
description Pepper (<i>Capsicum annuum</i>) is a globally important vegetable, and Verticillium wilt is an important disease affecting peppers and is caused by <i>Verticillium dahliae</i>, which can severely reduce yields. However, the molecular mechanisms underlying the responses of pepper to infection by <i>V. dahliae</i> are largely unknown. We performed physiological and transcriptome analysis using resistant and susceptible pepper cultivars inoculated with <i>V. dahliae</i>. Compared to the susceptible cultivar MS66, the resistant cultivar MS72 retained higher chlorophyll content and lower malondialdehyde content after inoculation. At 3 days after inoculation (DAI), compared with MS66, 534 differentially expressed genes (DEGs) were identified in MS72. At 5 DAI, 2392 DEGs were identified in MS72 compared with MS66. The DEGs in MS72 were mainly enriched in the cell wall and photosynthesis-related Gene Ontology terms, as well as in pathways such as cutin, suberin, wax biosynthesis, phenylpropanoid biosynthesis, and photosynthesis. Using weighted gene co-expression network analysis, 36 hub genes involved in the resistance response were identified, including the transcription factor <i>bHLH93</i> (Capana04g000815), defense-like protein 1 (MSTRG.5904), and miraculin-like (Capana10g002167). Our findings contribute to a more comprehensive understanding of the response mechanism of pepper to <i>V. dahliae</i> inoculation, providing new avenues for improving pepper resistance through breeding programs.
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spelling doaj-art-0807de8e8aec475e8b1b4333321885642025-08-20T01:53:56ZengMDPI AGHorticulturae2311-75242024-10-011011116010.3390/horticulturae10111160Transcriptome and Physiological Analyses of Resistant and Susceptible Pepper (<i>Capsicum annuum</i>) to <i>Verticillium dahliae</i> InoculumXinmin Huang0Liming He1Huimin Tan2Jiayi Liu3Qiucheng Qiu4Qidi Sun5Lejun Ouyang6Hanbing Han7Qinqin He8College of Biology and Food Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, ChinaCollege of Biology and Food Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, ChinaCollege of Biology and Food Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, ChinaCollege of Biology and Food Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, ChinaMaoming Maoshu Seed Industry Technology Co., Ltd., Maoming 525000, ChinaMaoming Maoshu Seed Industry Technology Co., Ltd., Maoming 525000, ChinaCollege of Biology and Food Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, ChinaCollege of Biology and Food Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, ChinaCollege of Biology and Food Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, ChinaPepper (<i>Capsicum annuum</i>) is a globally important vegetable, and Verticillium wilt is an important disease affecting peppers and is caused by <i>Verticillium dahliae</i>, which can severely reduce yields. However, the molecular mechanisms underlying the responses of pepper to infection by <i>V. dahliae</i> are largely unknown. We performed physiological and transcriptome analysis using resistant and susceptible pepper cultivars inoculated with <i>V. dahliae</i>. Compared to the susceptible cultivar MS66, the resistant cultivar MS72 retained higher chlorophyll content and lower malondialdehyde content after inoculation. At 3 days after inoculation (DAI), compared with MS66, 534 differentially expressed genes (DEGs) were identified in MS72. At 5 DAI, 2392 DEGs were identified in MS72 compared with MS66. The DEGs in MS72 were mainly enriched in the cell wall and photosynthesis-related Gene Ontology terms, as well as in pathways such as cutin, suberin, wax biosynthesis, phenylpropanoid biosynthesis, and photosynthesis. Using weighted gene co-expression network analysis, 36 hub genes involved in the resistance response were identified, including the transcription factor <i>bHLH93</i> (Capana04g000815), defense-like protein 1 (MSTRG.5904), and miraculin-like (Capana10g002167). Our findings contribute to a more comprehensive understanding of the response mechanism of pepper to <i>V. dahliae</i> inoculation, providing new avenues for improving pepper resistance through breeding programs.https://www.mdpi.com/2311-7524/10/11/1160pepperVerticillium wilt<i>Verticillium dahliae</i>chlorophyll contentmalondialdehyde concentrationdifferentially expressed genes
spellingShingle Xinmin Huang
Liming He
Huimin Tan
Jiayi Liu
Qiucheng Qiu
Qidi Sun
Lejun Ouyang
Hanbing Han
Qinqin He
Transcriptome and Physiological Analyses of Resistant and Susceptible Pepper (<i>Capsicum annuum</i>) to <i>Verticillium dahliae</i> Inoculum
Horticulturae
pepper
Verticillium wilt
<i>Verticillium dahliae</i>
chlorophyll content
malondialdehyde concentration
differentially expressed genes
title Transcriptome and Physiological Analyses of Resistant and Susceptible Pepper (<i>Capsicum annuum</i>) to <i>Verticillium dahliae</i> Inoculum
title_full Transcriptome and Physiological Analyses of Resistant and Susceptible Pepper (<i>Capsicum annuum</i>) to <i>Verticillium dahliae</i> Inoculum
title_fullStr Transcriptome and Physiological Analyses of Resistant and Susceptible Pepper (<i>Capsicum annuum</i>) to <i>Verticillium dahliae</i> Inoculum
title_full_unstemmed Transcriptome and Physiological Analyses of Resistant and Susceptible Pepper (<i>Capsicum annuum</i>) to <i>Verticillium dahliae</i> Inoculum
title_short Transcriptome and Physiological Analyses of Resistant and Susceptible Pepper (<i>Capsicum annuum</i>) to <i>Verticillium dahliae</i> Inoculum
title_sort transcriptome and physiological analyses of resistant and susceptible pepper i capsicum annuum i to i verticillium dahliae i inoculum
topic pepper
Verticillium wilt
<i>Verticillium dahliae</i>
chlorophyll content
malondialdehyde concentration
differentially expressed genes
url https://www.mdpi.com/2311-7524/10/11/1160
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