A Clinical and Confocal Microscopic Comparison of Transepithelial PRK and LASEK for Myopia
Purpose. To compare the clinical and confocal microscopic results of transepithelial PRK versus LASEK for correction of myopia. Materials and Methods. Twelve patients with myopia received transepithelial PRK in one eye and LASEK in the other. In transepithelial PRK-treated eyes, the corneal epithel...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/784185 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832565419254218752 |
|---|---|
| author | Safak Korkmaz Kamil Bilgihan Sabahattin Sul Ahmet Hondur |
| author_facet | Safak Korkmaz Kamil Bilgihan Sabahattin Sul Ahmet Hondur |
| author_sort | Safak Korkmaz |
| collection | DOAJ |
| description | Purpose. To compare the clinical and confocal microscopic results of transepithelial PRK versus LASEK for correction of myopia.
Materials and Methods. Twelve patients with myopia received transepithelial PRK in one eye and LASEK in the other. In transepithelial PRK-treated eyes, the corneal epithelium was removed with 40 microns of excimer laser ablation and in LASEK-treated eyes with 25-second application of 18% ethanol. Time to epithelial healing, ocular discomfort, uncorrected and best corrected visual acuities, manifest refraction, haze, greyscale value, and keratocyte apoptosis in confocal microscopy were recorded.
Results. The mean time to epithelial healing was significantly longer after LASEK (4.00 ± 0.43 versus 3.17 ± 0.6 days). On day 1, ocular discomfort was significantly higher after transepithelial PRK. The grade of haze, keratocyte apoptosis, and greyscale value in confocal microscopy were significantly higher in transepithelial PRK-treated eyes at 1 month. All transepithelial PRK- and LASEK-treated eyes achieved 20/25 or better UCVA and were within ±1.00 D of emmetropia at final visits. Conclusions. Both transepithelial PRK and LASEK offer effective correction of myopia at 1 year. However, LASEK appeared to induce less discomfort and less intense wound healing in the early postoperative period. |
| format | Article |
| id | doaj-art-0802359f5fde4c74a0afb6c21a89c145 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-0802359f5fde4c74a0afb6c21a89c1452025-02-03T01:07:44ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/784185784185A Clinical and Confocal Microscopic Comparison of Transepithelial PRK and LASEK for MyopiaSafak Korkmaz0Kamil Bilgihan1Sabahattin Sul2Ahmet Hondur3Department of Ophthalmology, Düzce State Hospital, Düzce, TurkeyDepartment of Ophthalmology, Gazi University Medical School, Ankara, TurkeyDepartment of Ophthalmology, Yatağan State Hospital, 48500 Muğla, TurkeyDepartment of Ophthalmology, Gazi University Medical School, Ankara, TurkeyPurpose. To compare the clinical and confocal microscopic results of transepithelial PRK versus LASEK for correction of myopia. Materials and Methods. Twelve patients with myopia received transepithelial PRK in one eye and LASEK in the other. In transepithelial PRK-treated eyes, the corneal epithelium was removed with 40 microns of excimer laser ablation and in LASEK-treated eyes with 25-second application of 18% ethanol. Time to epithelial healing, ocular discomfort, uncorrected and best corrected visual acuities, manifest refraction, haze, greyscale value, and keratocyte apoptosis in confocal microscopy were recorded. Results. The mean time to epithelial healing was significantly longer after LASEK (4.00 ± 0.43 versus 3.17 ± 0.6 days). On day 1, ocular discomfort was significantly higher after transepithelial PRK. The grade of haze, keratocyte apoptosis, and greyscale value in confocal microscopy were significantly higher in transepithelial PRK-treated eyes at 1 month. All transepithelial PRK- and LASEK-treated eyes achieved 20/25 or better UCVA and were within ±1.00 D of emmetropia at final visits. Conclusions. Both transepithelial PRK and LASEK offer effective correction of myopia at 1 year. However, LASEK appeared to induce less discomfort and less intense wound healing in the early postoperative period.http://dx.doi.org/10.1155/2014/784185 |
| spellingShingle | Safak Korkmaz Kamil Bilgihan Sabahattin Sul Ahmet Hondur A Clinical and Confocal Microscopic Comparison of Transepithelial PRK and LASEK for Myopia Journal of Ophthalmology |
| title | A Clinical and Confocal Microscopic Comparison of Transepithelial PRK and LASEK for Myopia |
| title_full | A Clinical and Confocal Microscopic Comparison of Transepithelial PRK and LASEK for Myopia |
| title_fullStr | A Clinical and Confocal Microscopic Comparison of Transepithelial PRK and LASEK for Myopia |
| title_full_unstemmed | A Clinical and Confocal Microscopic Comparison of Transepithelial PRK and LASEK for Myopia |
| title_short | A Clinical and Confocal Microscopic Comparison of Transepithelial PRK and LASEK for Myopia |
| title_sort | clinical and confocal microscopic comparison of transepithelial prk and lasek for myopia |
| url | http://dx.doi.org/10.1155/2014/784185 |
| work_keys_str_mv | AT safakkorkmaz aclinicalandconfocalmicroscopiccomparisonoftransepithelialprkandlasekformyopia AT kamilbilgihan aclinicalandconfocalmicroscopiccomparisonoftransepithelialprkandlasekformyopia AT sabahattinsul aclinicalandconfocalmicroscopiccomparisonoftransepithelialprkandlasekformyopia AT ahmethondur aclinicalandconfocalmicroscopiccomparisonoftransepithelialprkandlasekformyopia AT safakkorkmaz clinicalandconfocalmicroscopiccomparisonoftransepithelialprkandlasekformyopia AT kamilbilgihan clinicalandconfocalmicroscopiccomparisonoftransepithelialprkandlasekformyopia AT sabahattinsul clinicalandconfocalmicroscopiccomparisonoftransepithelialprkandlasekformyopia AT ahmethondur clinicalandconfocalmicroscopiccomparisonoftransepithelialprkandlasekformyopia |