Effectiveness of antimicrobial agent combinations against carbapenem-producing Klebsiella pneumoniae with KPC variants in China

Effectiveness of antimicrobial agent combinations against carbapenem-producing Klebsiella pneumoniae with KPC variants in China

PurposeCarbapenem-resistant Klebsiella pneumoniae (CRKP) producing carbapenemases poses a global threat to public health. Antimicrobial agent combinations have been promoted as a potential therapeutic strategy for infections. The most effective antimicrobial combinations against CRKP strains produci...

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Bibliographic Details
Main Authors: Congcong Liu, Yuchen Wu, Yanyan Zhang, Zelin Yan, Danxia Gu, Hongwei Zhou, Ning Dong, Chang Cai, Gongxiang Chen, Rong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Microbiology
Subjects:
carbapenem-resistant Klebsiella pneumoniae
checkerboard assay
antimicrobial agent combinations
KPC variant
ceftazidime/avibactam-based dual combinations
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1519319/full
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