SIRT1-dependent mechanisms and effects of resveratrol for amelioration of muscle wasting in NASH mice

SIRT1-dependent mechanisms and effects of resveratrol for amelioration of muscle wasting in NASH mice

Background In non-alcoholic steatohepatitis (NASH), muscle wasting was an aggravating factor for the progression of hepatic steatosis. This study explores the potential benefits of chronic treatment with resveratrol, a strong activator of SIRT1 on the muscle wasting of NASH mice.Methods In vivo and...

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Main Authors: Chang-Youh Tsai, Tzu-Hao Li, Ying-Ying Yang, Chia-Chang Huang, Chih-Wei Liu, Ming-Wei Lin, Ming-Chih Hou, Yi-Hsiang Huang, Chien-Fu Hsu, Yu-Lien Tsai, Hung-Cheng Tsai, Shiang-Fen Huang, Yun-Cheng Hsieh, Tzung-Yan Lee, Han-Chieh Lin
Format: Article
Language:English
Published: BMJ Publishing Group 2020-12-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/7/1/e000381.full
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