“Spice” (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case Series

Marijuana is the most widely abused “recreational” substance in the United States, with highest prevalence in young adults. It is reported to cause ischemic strokes, hepatitis, anxiety, and psychosis. Although it is associated with dose dependent tachycardia and can lead to coronary vasospasm, it ha...

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Main Authors: E. Ul Haq, A. Shafiq, A. A. Khan, A. A. Awan, S. Ezad, W. J. Minteer, B. Omar
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2017/9252463
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author E. Ul Haq
A. Shafiq
A. A. Khan
A. A. Awan
S. Ezad
W. J. Minteer
B. Omar
author_facet E. Ul Haq
A. Shafiq
A. A. Khan
A. A. Awan
S. Ezad
W. J. Minteer
B. Omar
author_sort E. Ul Haq
collection DOAJ
description Marijuana is the most widely abused “recreational” substance in the United States, with highest prevalence in young adults. It is reported to cause ischemic strokes, hepatitis, anxiety, and psychosis. Although it is associated with dose dependent tachycardia and can lead to coronary vasospasm, it has not been directly related to acute myocardial infarction (AMI). Marijuana induced coronary vasospasm can result in endothelial denudation at the site of a vulnerable atherosclerotic plaque in response to hemodynamic stressors, potentially causing an AMI. Spice refers to herbal mixture with composition and effects similar to that of marijuana and therefore is referred to as “synthetic marijuana.” Herein, we report 3 cases of spice induced ST-segment elevation myocardial infarction. All patients were relatively young and had few or absolutely no risk factors for cardiovascular disease. All patients underwent emergent coronary angiography, with two needing stent placement and the third requiring only aspiration thrombectomy. Our case series emphasizes the importance of suspecting and investigating synthetic marijuana use in low risk young adults presenting with AMI.
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institution Kabale University
issn 2090-6404
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language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Cardiology
spelling doaj-art-07e2df555b4d401690ecdfbca8b7b6aa2025-02-03T01:32:11ZengWileyCase Reports in Cardiology2090-64042090-64122017-01-01201710.1155/2017/92524639252463“Spice” (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case SeriesE. Ul Haq0A. Shafiq1A. A. Khan2A. A. Awan3S. Ezad4W. J. Minteer5B. Omar6University of South Alabama, Mobile, AL, USASaint Luke’s Mid America Heart Institute, Kansas City, MO, USAJohn Hunter Hospital, Newcastle, NSW, AustraliaHattiesburg Clinic, Hattiesburg, MS, USAJohn Hunter Hospital, Newcastle, NSW, AustraliaAppalachian Regional Healthcare, Cardiology Department, Middlesboro, KY, USAUniversity of South Alabama, Mobile, AL, USAMarijuana is the most widely abused “recreational” substance in the United States, with highest prevalence in young adults. It is reported to cause ischemic strokes, hepatitis, anxiety, and psychosis. Although it is associated with dose dependent tachycardia and can lead to coronary vasospasm, it has not been directly related to acute myocardial infarction (AMI). Marijuana induced coronary vasospasm can result in endothelial denudation at the site of a vulnerable atherosclerotic plaque in response to hemodynamic stressors, potentially causing an AMI. Spice refers to herbal mixture with composition and effects similar to that of marijuana and therefore is referred to as “synthetic marijuana.” Herein, we report 3 cases of spice induced ST-segment elevation myocardial infarction. All patients were relatively young and had few or absolutely no risk factors for cardiovascular disease. All patients underwent emergent coronary angiography, with two needing stent placement and the third requiring only aspiration thrombectomy. Our case series emphasizes the importance of suspecting and investigating synthetic marijuana use in low risk young adults presenting with AMI.http://dx.doi.org/10.1155/2017/9252463
spellingShingle E. Ul Haq
A. Shafiq
A. A. Khan
A. A. Awan
S. Ezad
W. J. Minteer
B. Omar
“Spice” (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case Series
Case Reports in Cardiology
title “Spice” (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case Series
title_full “Spice” (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case Series
title_fullStr “Spice” (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case Series
title_full_unstemmed “Spice” (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case Series
title_short “Spice” (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case Series
title_sort spice synthetic marijuana induced acute myocardial infarction a case series
url http://dx.doi.org/10.1155/2017/9252463
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