Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circle
[Objective] To explore the effectiveness of applying the PDCA (Plan-Do-Check-Act) cycle to enhance the compatibility rate of five Rh blood group antigen phenotypes between donors and recipients across multiple hospital campuses. [Methods] Clinical blood transfusion data from May to July 2022 were se...
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Institute of Blood Transfusion of Chinese Academy of Medical Sciences
2025-01-01
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| Series: | Zhongguo shuxue zazhi |
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| Online Access: | https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.01.018&lang=en |
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| author | YING Qiming CHEN Luyan DONG Kedi HE Yiwen ZHAN Yating YANG Yexiaoqing ZHAO Feng LYU Dingfeng |
| author_facet | YING Qiming CHEN Luyan DONG Kedi HE Yiwen ZHAN Yating YANG Yexiaoqing ZHAO Feng LYU Dingfeng |
| author_sort | YING Qiming |
| collection | DOAJ |
| description | [Objective] To explore the effectiveness of applying the PDCA (Plan-Do-Check-Act) cycle to enhance the compatibility rate of five Rh blood group antigen phenotypes between donors and recipients across multiple hospital campuses. [Methods] Clinical blood transfusion data from May to July 2022 were selected. Specific improvement measures were formulated based on the survey results, and the PDCA cycle management model was implemented from August 2022. The post-intervention phase spanned from August 2022 to October 2023. The Rh phenotype compatibility rate, the detection rate of Rh system antibodies, and the proportion of Rh system antibodies among unexpected antibodies were compared between the pre-intervention phase (May to July 2022) and the post-intervention phase. [Results] After the continuous improvement with the PDCA cycle, the compatibility rate for the five Rh blood group antigen phenotypes between donors and recipients from August to October 2023 reached 81.90%, significantly higher than the 70.54% recorded during the pre-intervention phase (May to July 2022, P<0.01), and displayed a quarterly upward trend (β=0.028, P<0.05). The detection rate of Rh blood group system antibodies (β=-9.839×10-5, P<0.05) and its proportion among all detected antibodies (β=-0.022, P<0.05) showed a quarterly decreasing trend, both demonstrating a negative correlation with the enhanced compatibility rate (r values of -0.981 and -0.911, respectively; P<0.05). [Conclusion] The implementation of targeted measures through the PDCA cycle can effectively increase the compatibility rate of five Rh blood group antigen phenotypes between donors and recipients, reduce the occurrence of unexpected Rh blood group antibodies, thereby lowering the risk of transfusion and enhancing the quality and safety of medical care. |
| format | Article |
| id | doaj-art-07a845c10827440c886510e4fb8d81dc |
| institution | Kabale University |
| issn | 1004-549X |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | Institute of Blood Transfusion of Chinese Academy of Medical Sciences |
| record_format | Article |
| series | Zhongguo shuxue zazhi |
| spelling | doaj-art-07a845c10827440c886510e4fb8d81dc2025-01-27T01:46:12ZzhoInstitute of Blood Transfusion of Chinese Academy of Medical SciencesZhongguo shuxue zazhi1004-549X2025-01-0138110611110.13303/j.cjbt.issn.1004-549x.2025.01.0181004-549X(2025)1-0106-06Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circleYING Qiming0CHEN Luyan1DONG Kedi2HE Yiwen3ZHAN Yating4YANG Yexiaoqing5ZHAO Feng6LYU Dingfeng7Department of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo 315010, ChinaDepartment of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo 315010, ChinaDepartment of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo 315010, ChinaDepartment of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo 315010, ChinaDepartment of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo 315010, ChinaDepartment of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo 315010, ChinaDepartment of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo 315010, ChinaDepartment of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo 315010, China[Objective] To explore the effectiveness of applying the PDCA (Plan-Do-Check-Act) cycle to enhance the compatibility rate of five Rh blood group antigen phenotypes between donors and recipients across multiple hospital campuses. [Methods] Clinical blood transfusion data from May to July 2022 were selected. Specific improvement measures were formulated based on the survey results, and the PDCA cycle management model was implemented from August 2022. The post-intervention phase spanned from August 2022 to October 2023. The Rh phenotype compatibility rate, the detection rate of Rh system antibodies, and the proportion of Rh system antibodies among unexpected antibodies were compared between the pre-intervention phase (May to July 2022) and the post-intervention phase. [Results] After the continuous improvement with the PDCA cycle, the compatibility rate for the five Rh blood group antigen phenotypes between donors and recipients from August to October 2023 reached 81.90%, significantly higher than the 70.54% recorded during the pre-intervention phase (May to July 2022, P<0.01), and displayed a quarterly upward trend (β=0.028, P<0.05). The detection rate of Rh blood group system antibodies (β=-9.839×10-5, P<0.05) and its proportion among all detected antibodies (β=-0.022, P<0.05) showed a quarterly decreasing trend, both demonstrating a negative correlation with the enhanced compatibility rate (r values of -0.981 and -0.911, respectively; P<0.05). [Conclusion] The implementation of targeted measures through the PDCA cycle can effectively increase the compatibility rate of five Rh blood group antigen phenotypes between donors and recipients, reduce the occurrence of unexpected Rh blood group antibodies, thereby lowering the risk of transfusion and enhancing the quality and safety of medical care.https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.01.018&lang=enpdca cyclerh blood group systemantigenphenotypetransfusion compatibility rate |
| spellingShingle | YING Qiming CHEN Luyan DONG Kedi HE Yiwen ZHAN Yating YANG Yexiaoqing ZHAO Feng LYU Dingfeng Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circle Zhongguo shuxue zazhi pdca cycle rh blood group system antigen phenotype transfusion compatibility rate |
| title | Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circle |
| title_full | Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circle |
| title_fullStr | Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circle |
| title_full_unstemmed | Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circle |
| title_short | Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circle |
| title_sort | optimization of rh blood group antigen precision transfusion strategy across multiple hospital campuses by pdca circle |
| topic | pdca cycle rh blood group system antigen phenotype transfusion compatibility rate |
| url | https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.01.018&lang=en |
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