Sequence and protein three-dimensional structure analysis of a novel inter-allelic recombination allele B*35∶186 of HLA-B locus

Sequence and protein three-dimensional structure analysis of a novel inter-allelic recombination allele B*35∶186 of HLA-B locus

[Objective] To study the inter-allelic recombination event occurring in the HLA-B locus, and to evaluate the molecular genetic mechanisms of a novel HLA allele, predict and analyze the impact of its amino acid residue changes on the three-dimensional structure. [Methods] HLA typing was taken with po...

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Bibliographic Details
Main Authors: ZHANG Xu, LIN Fengqiu, LI Xiaofeng, LI Jianping
Format: Article
Language:zho
Published: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2025-03-01
Series:Zhongguo shuxue zazhi
Subjects:
hla-b antigen
b*35∶186
gene recombination
sequence analysis
analysis of protein three-dimensional structure
Online Access:https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.03.004&lang=en
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