State-of-the-Art Management of Complications of Myeloma and Its Treatment

Multiple myeloma is an incurable disease, although patient survival has increased with the availability of novel agents. Both multiple myeloma and its therapies often affect the renal, immune, skeletal, hematologic, and nervous systems. The resulting organ dysfunctions often impair the quality of li...

Full description

Saved in:
Bibliographic Details
Main Authors: Monique A. Hartley-Brown, Daniel M. Sullivan, Rachid Baz
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2010/343089
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832554541792362496
author Monique A. Hartley-Brown
Daniel M. Sullivan
Rachid Baz
author_facet Monique A. Hartley-Brown
Daniel M. Sullivan
Rachid Baz
author_sort Monique A. Hartley-Brown
collection DOAJ
description Multiple myeloma is an incurable disease, although patient survival has increased with the availability of novel agents. Both multiple myeloma and its therapies often affect the renal, immune, skeletal, hematologic, and nervous systems. The resulting organ dysfunctions often impair the quality of life of affected patients, complicate and limit subsequent therapies, and may result in significant mortality. Research on the treatment of complications of multiple myeloma has been limited; hence, preventative and management strategies for patients with these complications are heterogeneous and often based on anecdotal experience. In this paper, we review the effects of myeloma and the novel therapies on organ systems and suggest management strategies.
format Article
id doaj-art-079c15e81cfa4218a90b17f08566fb79
institution Kabale University
issn 1687-9104
1687-9112
language English
publishDate 2010-01-01
publisher Wiley
record_format Article
series Advances in Hematology
spelling doaj-art-079c15e81cfa4218a90b17f08566fb792025-02-03T05:51:10ZengWileyAdvances in Hematology1687-91041687-91122010-01-01201010.1155/2010/343089343089State-of-the-Art Management of Complications of Myeloma and Its TreatmentMonique A. Hartley-Brown0Daniel M. Sullivan1Rachid Baz2Blood and Marrow Transplant Department, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr, Tampa, FL 33612, USABlood and Marrow Transplant Department, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr, Tampa, FL 33612, USADepartment of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr, Tampa, FL 33612, USAMultiple myeloma is an incurable disease, although patient survival has increased with the availability of novel agents. Both multiple myeloma and its therapies often affect the renal, immune, skeletal, hematologic, and nervous systems. The resulting organ dysfunctions often impair the quality of life of affected patients, complicate and limit subsequent therapies, and may result in significant mortality. Research on the treatment of complications of multiple myeloma has been limited; hence, preventative and management strategies for patients with these complications are heterogeneous and often based on anecdotal experience. In this paper, we review the effects of myeloma and the novel therapies on organ systems and suggest management strategies.http://dx.doi.org/10.1155/2010/343089
spellingShingle Monique A. Hartley-Brown
Daniel M. Sullivan
Rachid Baz
State-of-the-Art Management of Complications of Myeloma and Its Treatment
Advances in Hematology
title State-of-the-Art Management of Complications of Myeloma and Its Treatment
title_full State-of-the-Art Management of Complications of Myeloma and Its Treatment
title_fullStr State-of-the-Art Management of Complications of Myeloma and Its Treatment
title_full_unstemmed State-of-the-Art Management of Complications of Myeloma and Its Treatment
title_short State-of-the-Art Management of Complications of Myeloma and Its Treatment
title_sort state of the art management of complications of myeloma and its treatment
url http://dx.doi.org/10.1155/2010/343089
work_keys_str_mv AT moniqueahartleybrown stateoftheartmanagementofcomplicationsofmyelomaanditstreatment
AT danielmsullivan stateoftheartmanagementofcomplicationsofmyelomaanditstreatment
AT rachidbaz stateoftheartmanagementofcomplicationsofmyelomaanditstreatment