Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients

Surgical site infections (SSI) of the abdominal wall in renal transplant recipients can on occasion require management with negative pressure wound therapy (NPWT). This is often successful, with a low risk of further complications. However, we describe three cases in which persistent or recurrent su...

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Main Authors: Susanna Lam, Ngee-Soon Lau, Jerome Martin Laurence, Deborah Jean Verran
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2019/2452857
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author Susanna Lam
Ngee-Soon Lau
Jerome Martin Laurence
Deborah Jean Verran
author_facet Susanna Lam
Ngee-Soon Lau
Jerome Martin Laurence
Deborah Jean Verran
author_sort Susanna Lam
collection DOAJ
description Surgical site infections (SSI) of the abdominal wall in renal transplant recipients can on occasion require management with negative pressure wound therapy (NPWT). This is often successful, with a low risk of further complications. However, we describe three cases in which persistent or recurrent surgical site sepsis occurred, whilst NPWT was being deployed in adults with either wound dehiscence or initial SSI. This type of complication in the setting of NPWT has not been previously described in renal transplant recipients. Our case series demonstrates that in immunosuppressed transplant recipients, there may be ineffective microbial or bacterial bioburden clearance associated with the NPWT, which can lead to further infections. Hence recognition for infections in renal transplant patients undergoing treatment with NPWT is vital; furthermore, aggressive management of sepsis control with early debridement, antimicrobial use, and reassessment of the use of wound dressing is necessary to reduce the morbidity associated with surgical site infections and NPWT.
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institution Kabale University
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series Case Reports in Transplantation
spelling doaj-art-077a0d818fee4c8297ab5610da8486bf2025-02-03T07:24:40ZengWileyCase Reports in Transplantation2090-69432090-69512019-01-01201910.1155/2019/24528572452857Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant RecipientsSusanna Lam0Ngee-Soon Lau1Jerome Martin Laurence2Deborah Jean Verran3Royal Prince Alfred Hospital, Department of Transplantation Services, Sydney, AustraliaRoyal Prince Alfred Hospital, Department of Transplantation Services, Sydney, AustraliaRoyal Prince Alfred Hospital, Department of Transplantation Services, Sydney, AustraliaRoyal Prince Alfred Hospital, Department of Transplantation Services, Sydney, AustraliaSurgical site infections (SSI) of the abdominal wall in renal transplant recipients can on occasion require management with negative pressure wound therapy (NPWT). This is often successful, with a low risk of further complications. However, we describe three cases in which persistent or recurrent surgical site sepsis occurred, whilst NPWT was being deployed in adults with either wound dehiscence or initial SSI. This type of complication in the setting of NPWT has not been previously described in renal transplant recipients. Our case series demonstrates that in immunosuppressed transplant recipients, there may be ineffective microbial or bacterial bioburden clearance associated with the NPWT, which can lead to further infections. Hence recognition for infections in renal transplant patients undergoing treatment with NPWT is vital; furthermore, aggressive management of sepsis control with early debridement, antimicrobial use, and reassessment of the use of wound dressing is necessary to reduce the morbidity associated with surgical site infections and NPWT.http://dx.doi.org/10.1155/2019/2452857
spellingShingle Susanna Lam
Ngee-Soon Lau
Jerome Martin Laurence
Deborah Jean Verran
Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients
Case Reports in Transplantation
title Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients
title_full Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients
title_fullStr Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients
title_full_unstemmed Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients
title_short Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients
title_sort surgical site infections complicating the use of negative pressure wound therapy in renal transplant recipients
url http://dx.doi.org/10.1155/2019/2452857
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