Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes?
Introduction Osteoarthritis (OA) is a worldwide, disabling condition, more prevalent in older people. Although anxiety and depression disorders are common in OA and may affect compliance with treatment, both disorders are still underrecognized and undertreated. The present study aimed to screen for...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2024-12-01
|
| Series: | Rheumatology |
| Subjects: | |
| Online Access: | https://reu.termedia.pl/Anxiety-and-depression-in-primary-knee-osteoarthritis-patients-are-they-related-to,195120,0,2.html |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832584768158433280 |
|---|---|
| author | Yasmin A. Abd Elhamid Ghada S. Elazkalany Marwa H. Niazy Angie Y. Afifi |
| author_facet | Yasmin A. Abd Elhamid Ghada S. Elazkalany Marwa H. Niazy Angie Y. Afifi |
| author_sort | Yasmin A. Abd Elhamid |
| collection | DOAJ |
| description | Introduction
Osteoarthritis (OA) is a worldwide, disabling condition, more prevalent in older people. Although anxiety and depression disorders are common in OA and may affect compliance with treatment, both disorders are still underrecognized and undertreated. The present study aimed to screen for anxiety and depression among patients with primary knee OA, and to study the relationship between Hospital Anxiety and Depression Scale (HADS) score and different disease parameters.
Material and methods
Fifty patients fulfilling primary knee OA classification criteria were recruited for the study, and 50 age- and sex-matched healthy individuals served as a control group. Medical history was taken, clinical examination was done, and pain intensity was assessed using the Visual Analogue Scale. The 6-minute walk test was used for functional status assessment, and plain X-ray knees were scored according to the Kellgren and Lawrence classification system. Participants completed the HADS questionnaire.
Results
Twenty-nine patients were female (58%) and 21 were male (42%). The mean HADS score was significantly higher in OA patients than controls ( p = 0.001). The mean HADS-A (Anxiety) score was statistically significantly higher in OA patients than controls ( p < 0.001). Anxiety was more frequent in patients (44%) than in controls (10%) ( p < 0.001). In regression analysis, female sex could be considered as a predictor for each of HADS-A and HADS-D (Depression) (b: 0.4, 0.3; t : 3.28, 2.2; p = 0.002, 0.03; CI: 1.3–5.6, 0.2–4.4), respectively, while knee giving way was considered as a predictor for HADS-A (b: 0.34, t : 2.8, p = 0.007, CI: 0.96–5.87).
Conclusions
The results of the present study showed that anxiety level rather than depression was significantly higher in patients with primary knee OA than in controls. Female sex could be considered as a predictor for each of HADS-A and HADS-D, while knee giving way was considered as a predictor for HADS-A. |
| format | Article |
| id | doaj-art-0779d4344cb54c32b6f069963b00554b |
| institution | Kabale University |
| issn | 0034-6233 2084-9834 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Rheumatology |
| spelling | doaj-art-0779d4344cb54c32b6f069963b00554b2025-01-27T11:21:26ZengTermedia Publishing HouseRheumatology0034-62332084-98342024-12-0162642142910.5114/reum/195120195120Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes?Yasmin A. Abd Elhamid0https://orcid.org/0009-0000-7414-6086Ghada S. Elazkalany1https://orcid.org/0000-0003-1390-3949Marwa H. Niazy2https://orcid.org/0000-0003-1107-3240Angie Y. Afifi3https://orcid.org/0000-0002-0168-8631Department of Rheumatology and Rehabilitation, Faculty of Medicine, Cairo University, Kasr Alainy Hospital, Cairo, EgyptDepartment of Rheumatology and Rehabilitation, Faculty of Medicine, Cairo University, Kasr Alainy Hospital, Cairo, EgyptDepartment of Rheumatology and Rehabilitation, Faculty of Medicine, Cairo University, Kasr Alainy Hospital, Cairo, EgyptDepartment of Rheumatology and Rehabilitation, Faculty of Medicine, Cairo University, Kasr Alainy Hospital, Cairo, EgyptIntroduction Osteoarthritis (OA) is a worldwide, disabling condition, more prevalent in older people. Although anxiety and depression disorders are common in OA and may affect compliance with treatment, both disorders are still underrecognized and undertreated. The present study aimed to screen for anxiety and depression among patients with primary knee OA, and to study the relationship between Hospital Anxiety and Depression Scale (HADS) score and different disease parameters. Material and methods Fifty patients fulfilling primary knee OA classification criteria were recruited for the study, and 50 age- and sex-matched healthy individuals served as a control group. Medical history was taken, clinical examination was done, and pain intensity was assessed using the Visual Analogue Scale. The 6-minute walk test was used for functional status assessment, and plain X-ray knees were scored according to the Kellgren and Lawrence classification system. Participants completed the HADS questionnaire. Results Twenty-nine patients were female (58%) and 21 were male (42%). The mean HADS score was significantly higher in OA patients than controls ( p = 0.001). The mean HADS-A (Anxiety) score was statistically significantly higher in OA patients than controls ( p < 0.001). Anxiety was more frequent in patients (44%) than in controls (10%) ( p < 0.001). In regression analysis, female sex could be considered as a predictor for each of HADS-A and HADS-D (Depression) (b: 0.4, 0.3; t : 3.28, 2.2; p = 0.002, 0.03; CI: 1.3–5.6, 0.2–4.4), respectively, while knee giving way was considered as a predictor for HADS-A (b: 0.34, t : 2.8, p = 0.007, CI: 0.96–5.87). Conclusions The results of the present study showed that anxiety level rather than depression was significantly higher in patients with primary knee OA than in controls. Female sex could be considered as a predictor for each of HADS-A and HADS-D, while knee giving way was considered as a predictor for HADS-A.https://reu.termedia.pl/Anxiety-and-depression-in-primary-knee-osteoarthritis-patients-are-they-related-to,195120,0,2.htmlanxietyhadsmental healthprimary knee oa |
| spellingShingle | Yasmin A. Abd Elhamid Ghada S. Elazkalany Marwa H. Niazy Angie Y. Afifi Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes? Rheumatology anxiety hads mental health primary knee oa |
| title | Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes? |
| title_full | Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes? |
| title_fullStr | Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes? |
| title_full_unstemmed | Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes? |
| title_short | Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes? |
| title_sort | anxiety and depression in primary knee osteoarthritis patients are they related to clinical features and radiographic changes |
| topic | anxiety hads mental health primary knee oa |
| url | https://reu.termedia.pl/Anxiety-and-depression-in-primary-knee-osteoarthritis-patients-are-they-related-to,195120,0,2.html |
| work_keys_str_mv | AT yasminaabdelhamid anxietyanddepressioninprimarykneeosteoarthritispatientsaretheyrelatedtoclinicalfeaturesandradiographicchanges AT ghadaselazkalany anxietyanddepressioninprimarykneeosteoarthritispatientsaretheyrelatedtoclinicalfeaturesandradiographicchanges AT marwahniazy anxietyanddepressioninprimarykneeosteoarthritispatientsaretheyrelatedtoclinicalfeaturesandradiographicchanges AT angieyafifi anxietyanddepressioninprimarykneeosteoarthritispatientsaretheyrelatedtoclinicalfeaturesandradiographicchanges |