Daratumumab treatment for kidney-involved light chain deposition disease prevents renal function progression: a case report with 3 years of follow-up and review of the literature

Daratumumab treatment for kidney-involved light chain deposition disease prevents renal function progression: a case report with 3 years of follow-up and review of the literature

Light chain deposition disease (LCDD) is a clonal plasma cell disorder characterized by the deposition of nonamyloid monoclonal light chains in multiple organs. It can affect various systems throughout the body, mainly the kidneys. Symptoms may include renal insufficiency, proteinuria, hematuria, an...

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Bibliographic Details
Main Authors: Xueying Chen, Jie Sun, Pingyan Shen, Zijin Chen, Wen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
light chain deposition disease
free light chain
daratumumab
renal function
proteinuria
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1466323/full
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