ASSESSMENT OF BACTERICIDAL ROLE OF EPIDERMAL MUCUS OF MAJOR CARPS AGAINST PATHOGENIC MICROBIAL STRAINS
This research evaluated the antimicrobial potential of mucus from major carps, specifically Cirrhinus mrigala and Labeo rohita, against Klebsiella pneumoniae and Escherichia coli. Fish weighing 300-350 grams were stoked and acclimated for 15 days, fed with commercially available diet at 4% of their...
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University of Zakho
2025-01-01
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| Series: | Science Journal of University of Zakho |
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| Online Access: | https://sjuoz.uoz.edu.krd/index.php/sjuoz/article/view/1410 |
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| author | Farkhanda Asad Shahzad Nasir Itrat Fatima Zeliha Selamoglu Aiman Nadeem Rafia Jamal Maryam Fatima Maimoona Mehmood |
| author_facet | Farkhanda Asad Shahzad Nasir Itrat Fatima Zeliha Selamoglu Aiman Nadeem Rafia Jamal Maryam Fatima Maimoona Mehmood |
| author_sort | Farkhanda Asad |
| collection | DOAJ |
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This research evaluated the antimicrobial potential of mucus from major carps, specifically Cirrhinus mrigala and Labeo rohita, against Klebsiella pneumoniae and Escherichia coli. Fish weighing 300-350 grams were stoked and acclimated for 15 days, fed with commercially available diet at 4% of their body weight. Fish were treated with KMnO4 solution to avoid any infection before mucus collection and collected mucus was stored at 4°C. Mucus extracts were screened for antibacterial potential using the agar well diffusion method, measuring antibacterial effects by the zone of inhibition (ZOI) in mm. L. rohita secreted more mucus than C. mrigala. The mucus appearance of L. rohita was highly viscous, while less viscous in C. mrigala. In L. rohita mucus, maximum antimicrobial efficiency was observed. Results showed greater efficacy in limiting the growth of E. coli with zone of inhibition (16mm). Mucus is a key defense against disease. Fish skin mucus can serve as an alternative to antibiotics for use in aquaculture and potentially for human application. As a natural product, it may help reduce problems associated with antibiotic resistance.
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| format | Article |
| id | doaj-art-077191db9e7c4c98af34b1f5448e156a |
| institution | Kabale University |
| issn | 2663-628X 2663-6298 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | University of Zakho |
| record_format | Article |
| series | Science Journal of University of Zakho |
| spelling | doaj-art-077191db9e7c4c98af34b1f5448e156a2025-01-18T02:33:04ZengUniversity of ZakhoScience Journal of University of Zakho2663-628X2663-62982025-01-0113110.25271/sjuoz.2025.13.1.1410ASSESSMENT OF BACTERICIDAL ROLE OF EPIDERMAL MUCUS OF MAJOR CARPS AGAINST PATHOGENIC MICROBIAL STRAINSFarkhanda Asad0Shahzad Nasir1Itrat Fatima2Zeliha Selamoglu3Aiman Nadeem4Rafia Jamal5Maryam Fatima6Maimoona Mehmood7Department of Zoology, Government College University Faisalabad, Faisalabad, Punjab, PakistanDepartment of Zoology, Government College University Faisalabad, Faisalabad, Punjab, PakistanDepartment of Zoology, Government College University Faisalabad, Faisalabad, Punjab, PakistanDepartment of Medical Biology, Medicine Faculty, Nigde Omer Halisdemir University, Nigde, Türkiye.Department of Zoology, Government College University Faisalabad, Faisalabad, Punjab, PakistanDepartment of Zoology, Government College University Faisalabad, Faisalabad, Punjab, PakistanDepartment of Zoology, Government College University Faisalabad, Faisalabad, Punjab, PakistanDepartment of Zoology, Government College University Faisalabad, Faisalabad, Punjab, Pakistan This research evaluated the antimicrobial potential of mucus from major carps, specifically Cirrhinus mrigala and Labeo rohita, against Klebsiella pneumoniae and Escherichia coli. Fish weighing 300-350 grams were stoked and acclimated for 15 days, fed with commercially available diet at 4% of their body weight. Fish were treated with KMnO4 solution to avoid any infection before mucus collection and collected mucus was stored at 4°C. Mucus extracts were screened for antibacterial potential using the agar well diffusion method, measuring antibacterial effects by the zone of inhibition (ZOI) in mm. L. rohita secreted more mucus than C. mrigala. The mucus appearance of L. rohita was highly viscous, while less viscous in C. mrigala. In L. rohita mucus, maximum antimicrobial efficiency was observed. Results showed greater efficacy in limiting the growth of E. coli with zone of inhibition (16mm). Mucus is a key defense against disease. Fish skin mucus can serve as an alternative to antibiotics for use in aquaculture and potentially for human application. As a natural product, it may help reduce problems associated with antibiotic resistance. https://sjuoz.uoz.edu.krd/index.php/sjuoz/article/view/1410Fish |
| spellingShingle | Farkhanda Asad Shahzad Nasir Itrat Fatima Zeliha Selamoglu Aiman Nadeem Rafia Jamal Maryam Fatima Maimoona Mehmood ASSESSMENT OF BACTERICIDAL ROLE OF EPIDERMAL MUCUS OF MAJOR CARPS AGAINST PATHOGENIC MICROBIAL STRAINS Science Journal of University of Zakho Fish |
| title | ASSESSMENT OF BACTERICIDAL ROLE OF EPIDERMAL MUCUS OF MAJOR CARPS AGAINST PATHOGENIC MICROBIAL STRAINS |
| title_full | ASSESSMENT OF BACTERICIDAL ROLE OF EPIDERMAL MUCUS OF MAJOR CARPS AGAINST PATHOGENIC MICROBIAL STRAINS |
| title_fullStr | ASSESSMENT OF BACTERICIDAL ROLE OF EPIDERMAL MUCUS OF MAJOR CARPS AGAINST PATHOGENIC MICROBIAL STRAINS |
| title_full_unstemmed | ASSESSMENT OF BACTERICIDAL ROLE OF EPIDERMAL MUCUS OF MAJOR CARPS AGAINST PATHOGENIC MICROBIAL STRAINS |
| title_short | ASSESSMENT OF BACTERICIDAL ROLE OF EPIDERMAL MUCUS OF MAJOR CARPS AGAINST PATHOGENIC MICROBIAL STRAINS |
| title_sort | assessment of bactericidal role of epidermal mucus of major carps against pathogenic microbial strains |
| topic | Fish |
| url | https://sjuoz.uoz.edu.krd/index.php/sjuoz/article/view/1410 |
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