Evaluation of the Arabin cervical pessary for prevention of preterm birth in women with a twin pregnancy and short cervix (STOPPIT-2): An open-label randomised trial and updated meta-analysis.

Evaluation of the Arabin cervical pessary for prevention of preterm birth in women with a twin pregnancy and short cervix (STOPPIT-2): An open-label randomised trial and updated meta-analysis.

<h4>Background</h4>Preterm-labour-associated preterm birth is a common cause of perinatal mortality and morbidity in twin pregnancy. We aimed to test the hypothesis that the Arabin pessary would reduce preterm-labour-associated preterm birth by 40% or greater in women with a twin pregnan...

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Main Authors: Jane E Norman, John Norrie, Graeme MacLennan, David Cooper, Sonia Whyte, Sue Chowdhry, Sarah Cunningham-Burley, Xue W Mei, Joel B E Smith, Andrew Shennan, Stephen C Robson, Steven Thornton, Mark D Kilby, Neil Marlow, Sarah J Stock, Phillip R Bennett, Jane Denton, STOPPIT-2 collaborative group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003506
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