Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1
Neurofibromatosis type 1 (NF1) has been associated with an increased risk for development of malignancy, especially malignant peripheral nerve sheath tumors. In addition, recently, literature has demonstrated an increased risk of breast cancer in women with NF1. The present paper shows a 53-year-old...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/719061 |
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| author | Ana Paula Molina Vivas Luana Eschholz Bomfin Clovis Antonio Lopes Pinto Ulisses Ribaldo Nicolau Fabio Abreu Alves |
| author_facet | Ana Paula Molina Vivas Luana Eschholz Bomfin Clovis Antonio Lopes Pinto Ulisses Ribaldo Nicolau Fabio Abreu Alves |
| author_sort | Ana Paula Molina Vivas |
| collection | DOAJ |
| description | Neurofibromatosis type 1 (NF1) has been associated with an increased risk for development of malignancy, especially malignant peripheral nerve sheath tumors. In addition, recently, literature has demonstrated an increased risk of breast cancer in women with NF1. The present paper shows a 53-year-old woman with NF1 who presented with metaplastic breast carcinoma and developed multiple metastases, including mandible. Furthermore, we reviewed the English literature, found 63 cases showing the association between NF1 and breast cancer, and added one more case. The present study demonstrated an important association between NF1 and breast cancer. Until the present time, there has been only one case of metaplastic breast carcinoma associated with NF1. Curiously, in our case the oral metastasis corresponded to sarcomatous component of metaplastic breast carcinoma. |
| format | Article |
| id | doaj-art-075ae4c2b540461a972318b7b98f8014 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-075ae4c2b540461a972318b7b98f80142025-02-03T06:01:06ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/719061719061Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1Ana Paula Molina Vivas0Luana Eschholz Bomfin1Clovis Antonio Lopes Pinto2Ulisses Ribaldo Nicolau3Fabio Abreu Alves4Stomatology Department, A.C. Camargo Cancer Center, Rua Professor Antonio Prudente 211, 01509-900 São Paulo, SP, BrazilStomatology Department, University of São Paulo, Avenida Professor Lineu Prestes 2227, 05508-000 São Paulo, SP, BrazilPathology Department, A.C. Camargo Cancer Center, Rua Professor Antonio Prudente 211, 01509-900 São Paulo, SP, BrazilClinical Oncology Department, A.C. Camargo Cancer Center, Rua Professor Antonio Prudente 211, 01509-900 São Paulo, SP, BrazilStomatology Department, A.C. Camargo Cancer Center, Rua Professor Antonio Prudente 211, 01509-900 São Paulo, SP, BrazilNeurofibromatosis type 1 (NF1) has been associated with an increased risk for development of malignancy, especially malignant peripheral nerve sheath tumors. In addition, recently, literature has demonstrated an increased risk of breast cancer in women with NF1. The present paper shows a 53-year-old woman with NF1 who presented with metaplastic breast carcinoma and developed multiple metastases, including mandible. Furthermore, we reviewed the English literature, found 63 cases showing the association between NF1 and breast cancer, and added one more case. The present study demonstrated an important association between NF1 and breast cancer. Until the present time, there has been only one case of metaplastic breast carcinoma associated with NF1. Curiously, in our case the oral metastasis corresponded to sarcomatous component of metaplastic breast carcinoma.http://dx.doi.org/10.1155/2014/719061 |
| spellingShingle | Ana Paula Molina Vivas Luana Eschholz Bomfin Clovis Antonio Lopes Pinto Ulisses Ribaldo Nicolau Fabio Abreu Alves Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1 Case Reports in Oncological Medicine |
| title | Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1 |
| title_full | Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1 |
| title_fullStr | Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1 |
| title_full_unstemmed | Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1 |
| title_short | Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1 |
| title_sort | oral metastasis of metaplastic breast carcinoma in a patient with neurofibromatosis 1 |
| url | http://dx.doi.org/10.1155/2014/719061 |
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