Oligometastatic Disease at Presentation or Recurrence for Nonsmall Cell Lung Cancer

Oligometastatic Non-Small Cell Lung Cancer (NSCLC) presents a unique opportunity for potential curative therapy. Improved cancer staging using PET/CT, MRI, and future cellular and molecular staging with circulating tumor cells and/or molecular markers will identify more patients with truly oligometa...

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Main Authors: Daniel R. Gomez, Yuzuru Niibe, Joe Y. Chang
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Pulmonary Medicine
Online Access:http://dx.doi.org/10.1155/2012/396592
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author Daniel R. Gomez
Yuzuru Niibe
Joe Y. Chang
author_facet Daniel R. Gomez
Yuzuru Niibe
Joe Y. Chang
author_sort Daniel R. Gomez
collection DOAJ
description Oligometastatic Non-Small Cell Lung Cancer (NSCLC) presents a unique opportunity for potential curative therapy. Improved cancer staging using PET/CT, MRI, and future cellular and molecular staging with circulating tumor cells and/or molecular markers will identify more patients with truly oligometastasis disease that will benefit from definitive local treatment. Recent development of noninvasive local ablative therapy such as stereotactic radiotherapy makes it possible to eradicate multiple local diseases with minimal side effect. Novel systemic therapy may also control systemic spread and therefore make it possible to improve survival by eliminating local diseases. More research, particularly prospective studies, is ideally randomized studies are needed to validate the concept of oligometastasis.
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series Pulmonary Medicine
spelling doaj-art-073ba3c5f706454cad95004aa2d63b8b2025-02-03T00:59:26ZengWileyPulmonary Medicine2090-18362090-18442012-01-01201210.1155/2012/396592396592Oligometastatic Disease at Presentation or Recurrence for Nonsmall Cell Lung CancerDaniel R. Gomez0Yuzuru Niibe1Joe Y. Chang2Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Unit 0097, TX 77030, USADepartment of Radiology and Radiation Oncology, Kitasato University School of Medicine, Sagamihara 252-0374, JapanDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Unit 0097, TX 77030, USAOligometastatic Non-Small Cell Lung Cancer (NSCLC) presents a unique opportunity for potential curative therapy. Improved cancer staging using PET/CT, MRI, and future cellular and molecular staging with circulating tumor cells and/or molecular markers will identify more patients with truly oligometastasis disease that will benefit from definitive local treatment. Recent development of noninvasive local ablative therapy such as stereotactic radiotherapy makes it possible to eradicate multiple local diseases with minimal side effect. Novel systemic therapy may also control systemic spread and therefore make it possible to improve survival by eliminating local diseases. More research, particularly prospective studies, is ideally randomized studies are needed to validate the concept of oligometastasis.http://dx.doi.org/10.1155/2012/396592
spellingShingle Daniel R. Gomez
Yuzuru Niibe
Joe Y. Chang
Oligometastatic Disease at Presentation or Recurrence for Nonsmall Cell Lung Cancer
Pulmonary Medicine
title Oligometastatic Disease at Presentation or Recurrence for Nonsmall Cell Lung Cancer
title_full Oligometastatic Disease at Presentation or Recurrence for Nonsmall Cell Lung Cancer
title_fullStr Oligometastatic Disease at Presentation or Recurrence for Nonsmall Cell Lung Cancer
title_full_unstemmed Oligometastatic Disease at Presentation or Recurrence for Nonsmall Cell Lung Cancer
title_short Oligometastatic Disease at Presentation or Recurrence for Nonsmall Cell Lung Cancer
title_sort oligometastatic disease at presentation or recurrence for nonsmall cell lung cancer
url http://dx.doi.org/10.1155/2012/396592
work_keys_str_mv AT danielrgomez oligometastaticdiseaseatpresentationorrecurrencefornonsmallcelllungcancer
AT yuzuruniibe oligometastaticdiseaseatpresentationorrecurrencefornonsmallcelllungcancer
AT joeychang oligometastaticdiseaseatpresentationorrecurrencefornonsmallcelllungcancer