Analysis of HIV therapy in the liver using optimal control and pharmacokinetics

Analysis of HIV therapy in the liver using optimal control and pharmacokinetics

Abstract The main burden in treating human immunodeficiency virus (HIV) infection currently, is the side effects of the antiretroviral therapy (ART) used, because each treatment is toxic to the liver. This study uses optimal control theory applied to a mathematical model that describes the dynamics...

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Bibliographic Details
Main Authors: Hasifa Nampala, Matylda Jabłońska-Sabuka, Martin Singull
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Journal of Mathematics in Industry
Subjects:
HIV
Antiretroviral therapy
Optimal control
Pharmacokinetics
Online Access:https://doi.org/10.1186/s13362-025-00167-y
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