Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency

Introduction. Naphthalene is an aromatic hydrocarbon that may be found in mothballs and deodorizers. Exposure can occur by ingestion or dermal absorption. We present a case of acute hemolysis requiring blood transfusion in a 21-month-old male with a history of glucose-6-phosphate dehydrogenase (G6PD...

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Main Authors: Maricel Dela Cruz, Muhammad Masood Khalid, Ahmed Mostafa, Muhammed Ershad, David Vearrier, Rita McKeever
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2019/1092575
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author Maricel Dela Cruz
Muhammad Masood Khalid
Ahmed Mostafa
Muhammed Ershad
David Vearrier
Rita McKeever
author_facet Maricel Dela Cruz
Muhammad Masood Khalid
Ahmed Mostafa
Muhammed Ershad
David Vearrier
Rita McKeever
author_sort Maricel Dela Cruz
collection DOAJ
description Introduction. Naphthalene is an aromatic hydrocarbon that may be found in mothballs and deodorizers. Exposure can occur by ingestion or dermal absorption. We present a case of acute hemolysis requiring blood transfusion in a 21-month-old male with a history of glucose-6-phosphate dehydrogenase (G6PD) deficiency after ingestion of a naphthalene-containing mothball. Case Presentation. A 21-month-old male with G6PD deficiency presented to the emergency department three hours following an exploratory ingestion of a naphthalene-containing mothball. On arrival, the patient was tachycardic with normal blood pressure, temperature, respiratory rate, and oxygen saturation. Initial laboratory studies showed significant anemia with elevated reticulocyte count, blood urea nitrogen, total bilirubin, and lactate dehydrogenase. Haptoglobin level was low, and the methemoglobin level was unremarkable. The patient was admitted to the pediatric intensive care unit and underwent blood transfusion. Discussion. This case serves as a reminder that mothballs, a ubiquitous household item, can be hazardous when accessible to vulnerable children. Care should be taken to secure these products and prevent ingestion.
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publishDate 2019-01-01
publisher Wiley
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series Case Reports in Pediatrics
spelling doaj-art-06fee124865e4831b90d4897eb4776912025-02-03T06:08:08ZengWileyCase Reports in Pediatrics2090-68032090-68112019-01-01201910.1155/2019/10925751092575Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) DeficiencyMaricel Dela Cruz0Muhammad Masood Khalid1Ahmed Mostafa2Muhammed Ershad3David Vearrier4Rita McKeever5Department of Emergency Medicine, Division of Medical Toxicology, Drexel University College of Medicine, 245 N 15th Street, MS 1011, Philadelphia, PA 19102, USADepartment of Emergency Medicine, Division of Medical Toxicology, Drexel University College of Medicine, 245 N 15th Street, MS 1011, Philadelphia, PA 19102, USADepartment of Emergency Medicine, Division of Medical Toxicology, Drexel University College of Medicine, 245 N 15th Street, MS 1011, Philadelphia, PA 19102, USADepartment of Emergency Medicine, Division of Medical Toxicology, Drexel University College of Medicine, 245 N 15th Street, MS 1011, Philadelphia, PA 19102, USADepartment of Emergency Medicine, Division of Medical Toxicology, Drexel University College of Medicine, 245 N 15th Street, MS 1011, Philadelphia, PA 19102, USADepartment of Emergency Medicine, Division of Medical Toxicology, Drexel University College of Medicine, 245 N 15th Street, MS 1011, Philadelphia, PA 19102, USAIntroduction. Naphthalene is an aromatic hydrocarbon that may be found in mothballs and deodorizers. Exposure can occur by ingestion or dermal absorption. We present a case of acute hemolysis requiring blood transfusion in a 21-month-old male with a history of glucose-6-phosphate dehydrogenase (G6PD) deficiency after ingestion of a naphthalene-containing mothball. Case Presentation. A 21-month-old male with G6PD deficiency presented to the emergency department three hours following an exploratory ingestion of a naphthalene-containing mothball. On arrival, the patient was tachycardic with normal blood pressure, temperature, respiratory rate, and oxygen saturation. Initial laboratory studies showed significant anemia with elevated reticulocyte count, blood urea nitrogen, total bilirubin, and lactate dehydrogenase. Haptoglobin level was low, and the methemoglobin level was unremarkable. The patient was admitted to the pediatric intensive care unit and underwent blood transfusion. Discussion. This case serves as a reminder that mothballs, a ubiquitous household item, can be hazardous when accessible to vulnerable children. Care should be taken to secure these products and prevent ingestion.http://dx.doi.org/10.1155/2019/1092575
spellingShingle Maricel Dela Cruz
Muhammad Masood Khalid
Ahmed Mostafa
Muhammed Ershad
David Vearrier
Rita McKeever
Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
Case Reports in Pediatrics
title Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
title_full Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
title_fullStr Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
title_full_unstemmed Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
title_short Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
title_sort hemolytic crisis following naphthalene mothball ingestion in a 21 month old patient with glucose 6 phosphate dehydrogenase g6pd deficiency
url http://dx.doi.org/10.1155/2019/1092575
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