Measurement of macrophage phagocytic capacity by quantifying maximum membrane extension using an opsonized capillary tube assay

Abstract The zipper mechanism explains phagocytosis as sequential ligand–receptor interactions between macrophages and antigens, followed by the cell membrane extension for phagosome formation. Hence, the ability of macrophages to innate immunity is restricted by their capacity for engulfment relate...

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Bibliographic Details
Main Authors: Dan Horonushi, Souta Suzuki, Maiha Ando, Haruka Yuki, Kenji Yasuda
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-03655-8
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