Congenital Microphthalmic Syndrome in a Swine
A 17-week-old crossbred finishing pig was presented for lameness of approximately one week. Clinical evaluation, including ophthalmologic examination, revealed ataxia, partial flaccid paresis of the pelvic limbs, skin lesions at feet and claws, and severely reduced vision/blindness. Both eyes had mu...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Veterinary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/2051350 |
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| author | Radka Andrysikova Titus Sydler Dolf Kümmerlen Wolfgang Pendl Robert Graage Romana Moutelikova Jana Prodelalova Katrin Voelter |
| author_facet | Radka Andrysikova Titus Sydler Dolf Kümmerlen Wolfgang Pendl Robert Graage Romana Moutelikova Jana Prodelalova Katrin Voelter |
| author_sort | Radka Andrysikova |
| collection | DOAJ |
| description | A 17-week-old crossbred finishing pig was presented for lameness of approximately one week. Clinical evaluation, including ophthalmologic examination, revealed ataxia, partial flaccid paresis of the pelvic limbs, skin lesions at feet and claws, and severely reduced vision/blindness. Both eyes had multiple persistent pupillary membranes (iris-to-iris and iris-to-lens) and hypermature cataracts. Histopathological examination of the eyes revealed microphthalmia, microphakia with cataract formation, myovascularised membrane in the vitreous, retinal detachment, and retinal dysplasia. Microscopic examination of tissues collected postmortem demonstrated nonsuppurative polioencephalomyelitis with the most prominent inflammatory lesions in the lumbar spinal cord. Subsequently, presumed Teschen/Talfan disease was confirmed by porcine teschovirus identification in the spinal cord using the reverse transcription-polymerase chain reaction (RT-PCR). To the authors’ knowledge, this is the first case report describing in detail histopathological changes in the porcine congenital microphthalmic syndrome. |
| format | Article |
| id | doaj-art-06e90d8f6f7b47c6b1b88a39eb954f27 |
| institution | OA Journals |
| issn | 2090-7001 2090-701X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Veterinary Medicine |
| spelling | doaj-art-06e90d8f6f7b47c6b1b88a39eb954f272025-08-20T02:02:51ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2018-01-01201810.1155/2018/20513502051350Congenital Microphthalmic Syndrome in a SwineRadka Andrysikova0Titus Sydler1Dolf Kümmerlen2Wolfgang Pendl3Robert Graage4Romana Moutelikova5Jana Prodelalova6Katrin Voelter7Equine Department, Section of Ophthalmology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zürich, SwitzerlandInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 270, 8057 Zürich, SwitzerlandDepartment for Farm Animals, Division of Swine Medicine, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 270, 8057 Zürich, SwitzerlandDepartment for Farm Animals, Division of Swine Medicine, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 270, 8057 Zürich, SwitzerlandDepartment for Farm Animals, Division of Swine Medicine, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 270, 8057 Zürich, SwitzerlandVeterinary Research Institute, Hudcova 296/70, 621 00 Brno, Czech RepublicVeterinary Research Institute, Hudcova 296/70, 621 00 Brno, Czech RepublicEquine Department, Section of Ophthalmology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zürich, SwitzerlandA 17-week-old crossbred finishing pig was presented for lameness of approximately one week. Clinical evaluation, including ophthalmologic examination, revealed ataxia, partial flaccid paresis of the pelvic limbs, skin lesions at feet and claws, and severely reduced vision/blindness. Both eyes had multiple persistent pupillary membranes (iris-to-iris and iris-to-lens) and hypermature cataracts. Histopathological examination of the eyes revealed microphthalmia, microphakia with cataract formation, myovascularised membrane in the vitreous, retinal detachment, and retinal dysplasia. Microscopic examination of tissues collected postmortem demonstrated nonsuppurative polioencephalomyelitis with the most prominent inflammatory lesions in the lumbar spinal cord. Subsequently, presumed Teschen/Talfan disease was confirmed by porcine teschovirus identification in the spinal cord using the reverse transcription-polymerase chain reaction (RT-PCR). To the authors’ knowledge, this is the first case report describing in detail histopathological changes in the porcine congenital microphthalmic syndrome.http://dx.doi.org/10.1155/2018/2051350 |
| spellingShingle | Radka Andrysikova Titus Sydler Dolf Kümmerlen Wolfgang Pendl Robert Graage Romana Moutelikova Jana Prodelalova Katrin Voelter Congenital Microphthalmic Syndrome in a Swine Case Reports in Veterinary Medicine |
| title | Congenital Microphthalmic Syndrome in a Swine |
| title_full | Congenital Microphthalmic Syndrome in a Swine |
| title_fullStr | Congenital Microphthalmic Syndrome in a Swine |
| title_full_unstemmed | Congenital Microphthalmic Syndrome in a Swine |
| title_short | Congenital Microphthalmic Syndrome in a Swine |
| title_sort | congenital microphthalmic syndrome in a swine |
| url | http://dx.doi.org/10.1155/2018/2051350 |
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