Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism
Prions are considered the best example to prove that the biological information can be transferred protein to protein through a conformational change. The term “prion-like” is used to describe molecular mechanisms that share similarities with the mammalian prion protein self-perpetuating aggregation...
Saved in:
| Main Authors: | Natalia Fernández-Borges, Hasier Eraña, Saioa R. Elezgarai, Chafik Harrathi, Mayela Gayosso, Joaquín Castilla |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | International Journal of Cell Biology |
| Online Access: | http://dx.doi.org/10.1155/2013/583498 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.
by: Claudia Stincardini, et al.
Published: (2017-01-01) -
Evidence for Prion-Like Mechanisms in Several Neurodegenerative Diseases: Potential Implications for Immunotherapy
by: Kristen Marciniuk, et al.
Published: (2013-01-01) -
The Prion Basis of Progressive Neurodegenerative Disorders
by: Tvisha Joshi, et al.
Published: (2023-01-01) -
Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions.
by: Miguel Ángel Pérez-Castro, et al.
Published: (2025-01-01) -
Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity
by: Carlos M. Díaz-Domínguez, et al.
Published: (2025-09-01)