FEATURES OF CLINICAL COURSE AND MORPHOLOGICAL CHANGES OF CHRONIC HEPATITIS C IN INFANTS
The authors have observed 37 young children with chronic viral hepatitis C of different route: perinatal — 24 children (group 1) and not perinatal — 13 patients (group 2). The clinical picture and morphological pattern of the infection depending on the route of the infection have been presented. In...
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| Language: | Russian |
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LLC "Diagnostics and Vaccines"
2015-08-01
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| Series: | Детские инфекции (Москва) |
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| Online Access: | https://detinf.elpub.ru/jour/article/view/152 |
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| author | M. M. Kotovich F. K. Manerov N. A. Karnauhova |
| author_facet | M. M. Kotovich F. K. Manerov N. A. Karnauhova |
| author_sort | M. M. Kotovich |
| collection | DOAJ |
| description | The authors have observed 37 young children with chronic viral hepatitis C of different route: perinatal — 24 children (group 1) and not perinatal — 13 patients (group 2). The clinical picture and morphological pattern of the infection depending on the route of the infection have been presented. In case of perinatal infection, some children showed physical developmental disabilities and malabsorption syndrome. The biochemical activity was predominantly minimal in group 1 and low in group 2. Histological changes in liver tissue were revealed in all the young children with chronic hepatitis C. However, the inflammatory activity in the liver tissue is more prominent in children of the group 2, and the degree of fibrosis is more prominent in children from group 1. Only in case of perinatal infection the direct correlation between elevated levels of ALT and AST and the presence of fibrosis in the liver tissue has been revealed revealed. |
| format | Article |
| id | doaj-art-06b8f3739d9e475c9a0fe506d2bc39d9 |
| institution | DOAJ |
| issn | 2072-8107 |
| language | Russian |
| publishDate | 2015-08-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj-art-06b8f3739d9e475c9a0fe506d2bc39d92025-08-20T03:15:22ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072015-08-01124313410.22627/2072-8107-2013-12-4-31-34152FEATURES OF CLINICAL COURSE AND MORPHOLOGICAL CHANGES OF CHRONIC HEPATITIS C IN INFANTSM. M. Kotovich0F. K. Manerov1N. A. Karnauhova2Novokuznetsk State Institute of Postgraduate MedicineNovokuznetsk State Institute of Postgraduate MedicineRepublican Clinical Hospital named after G.Ya. RemishevskfyaThe authors have observed 37 young children with chronic viral hepatitis C of different route: perinatal — 24 children (group 1) and not perinatal — 13 patients (group 2). The clinical picture and morphological pattern of the infection depending on the route of the infection have been presented. In case of perinatal infection, some children showed physical developmental disabilities and malabsorption syndrome. The biochemical activity was predominantly minimal in group 1 and low in group 2. Histological changes in liver tissue were revealed in all the young children with chronic hepatitis C. However, the inflammatory activity in the liver tissue is more prominent in children of the group 2, and the degree of fibrosis is more prominent in children from group 1. Only in case of perinatal infection the direct correlation between elevated levels of ALT and AST and the presence of fibrosis in the liver tissue has been revealed revealed.https://detinf.elpub.ru/jour/article/view/152chronic hepatitis cinfantsclinical and morphological changes |
| spellingShingle | M. M. Kotovich F. K. Manerov N. A. Karnauhova FEATURES OF CLINICAL COURSE AND MORPHOLOGICAL CHANGES OF CHRONIC HEPATITIS C IN INFANTS Детские инфекции (Москва) chronic hepatitis c infants clinical and morphological changes |
| title | FEATURES OF CLINICAL COURSE AND MORPHOLOGICAL CHANGES OF CHRONIC HEPATITIS C IN INFANTS |
| title_full | FEATURES OF CLINICAL COURSE AND MORPHOLOGICAL CHANGES OF CHRONIC HEPATITIS C IN INFANTS |
| title_fullStr | FEATURES OF CLINICAL COURSE AND MORPHOLOGICAL CHANGES OF CHRONIC HEPATITIS C IN INFANTS |
| title_full_unstemmed | FEATURES OF CLINICAL COURSE AND MORPHOLOGICAL CHANGES OF CHRONIC HEPATITIS C IN INFANTS |
| title_short | FEATURES OF CLINICAL COURSE AND MORPHOLOGICAL CHANGES OF CHRONIC HEPATITIS C IN INFANTS |
| title_sort | features of clinical course and morphological changes of chronic hepatitis c in infants |
| topic | chronic hepatitis c infants clinical and morphological changes |
| url | https://detinf.elpub.ru/jour/article/view/152 |
| work_keys_str_mv | AT mmkotovich featuresofclinicalcourseandmorphologicalchangesofchronichepatitiscininfants AT fkmanerov featuresofclinicalcourseandmorphologicalchangesofchronichepatitiscininfants AT nakarnauhova featuresofclinicalcourseandmorphologicalchangesofchronichepatitiscininfants |