Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism?
Background. Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by abnormal proliferation of the skin and bony structures at the distal extremities resulting in digital clubbing, periosteal bony reaction, and joint effusion. It can be primary (idiopathic) without any clear identifiable e...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2017/2583762 |
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| author | Yanal Alnimer Suresh Subedi Thair Dawood Ghassan Bachuwa |
| author_facet | Yanal Alnimer Suresh Subedi Thair Dawood Ghassan Bachuwa |
| author_sort | Yanal Alnimer |
| collection | DOAJ |
| description | Background. Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by abnormal proliferation of the skin and bony structures at the distal extremities resulting in digital clubbing, periosteal bony reaction, and joint effusion. It can be primary (idiopathic) without any clear identifiable etiology as well as secondary to variety of systemic diseases most notably lung pathology. Case Presentation. We describe a rare case of primary idiopathic osteoarthropathy in a male patient who presented with severe pain and tenderness in his legs. His history was significant for long standing alcoholism. Physical examination showed severe fingers and toes clubbing. He reported similar changes in his mother. Clinical and radiological findings were remarkable for distal leg tenderness and diffuse periosteal bony reactions, respectively. Computerized tomography scan failed to show any pathology apart from fatty liver infiltration. In the absence of obesity or diabetes, this was consistent with alcoholic steatosis. He was started on nonsteroidal anti-inflammatory drug which dramatically improved his symptoms. Conclusion. Primary hypertrophic osteoarthropathy should be considered in a previously healthy person presenting with bony pain and finger clubbing especially after ruling out the common secondary causes. Moreover, alteration of prostaglandin metabolism secondary to alcoholic consumption might be a contributing factor. |
| format | Article |
| id | doaj-art-06b6fe76c0d54857a0b080bc9e09ca1e |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-06b6fe76c0d54857a0b080bc9e09ca1e2025-02-03T05:46:21ZengWileyCase Reports in Rheumatology2090-68892090-68972017-01-01201710.1155/2017/25837622583762Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism?Yanal Alnimer0Suresh Subedi1Thair Dawood2Ghassan Bachuwa3Internal Medicine Department, Hurley Medical Center, Flint, MI, USAInternal Medicine Department, Hurley Medical Center, Flint, MI, USAInternal Medicine Department, Hurley Medical Center, Flint, MI, USAInternal Medicine Department, Hurley Medical Center, Flint, MI, USABackground. Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by abnormal proliferation of the skin and bony structures at the distal extremities resulting in digital clubbing, periosteal bony reaction, and joint effusion. It can be primary (idiopathic) without any clear identifiable etiology as well as secondary to variety of systemic diseases most notably lung pathology. Case Presentation. We describe a rare case of primary idiopathic osteoarthropathy in a male patient who presented with severe pain and tenderness in his legs. His history was significant for long standing alcoholism. Physical examination showed severe fingers and toes clubbing. He reported similar changes in his mother. Clinical and radiological findings were remarkable for distal leg tenderness and diffuse periosteal bony reactions, respectively. Computerized tomography scan failed to show any pathology apart from fatty liver infiltration. In the absence of obesity or diabetes, this was consistent with alcoholic steatosis. He was started on nonsteroidal anti-inflammatory drug which dramatically improved his symptoms. Conclusion. Primary hypertrophic osteoarthropathy should be considered in a previously healthy person presenting with bony pain and finger clubbing especially after ruling out the common secondary causes. Moreover, alteration of prostaglandin metabolism secondary to alcoholic consumption might be a contributing factor.http://dx.doi.org/10.1155/2017/2583762 |
| spellingShingle | Yanal Alnimer Suresh Subedi Thair Dawood Ghassan Bachuwa Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism? Case Reports in Rheumatology |
| title | Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism? |
| title_full | Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism? |
| title_fullStr | Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism? |
| title_full_unstemmed | Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism? |
| title_short | Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism? |
| title_sort | primary idiopathic osteoarthropathy could it be related to alcoholism |
| url | http://dx.doi.org/10.1155/2017/2583762 |
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