Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective Study
Purpose We prospectively compared the diagnostic accuracy of kidney dynamic computed tomography (KDCT), magnetic resonance imaging (MRI), and contrast-enhanced ultrasonography (CEUS) for the assessment of small renal mass (SRM) (≤4 cm). Materials and Methods Seventy-six patients with SRM (mean age,...
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Korean Urological Oncology Society
2024-07-01
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| Series: | Journal of Urologic Oncology |
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| Online Access: | http://www.e-juo.org/upload/pdf/juo-244800320016.pdf |
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| author | Jae-Wook Chung Seo Young Park Seunghee Woo Yun Ah Kim Jun-Koo Kang Yun-Sok Ha Jun Nyung Lee Bum Soo Kim Tae-Hwan Kim Ghil Suk Yoon Tae Gyun Kwon See Hyung Kim |
| author_facet | Jae-Wook Chung Seo Young Park Seunghee Woo Yun Ah Kim Jun-Koo Kang Yun-Sok Ha Jun Nyung Lee Bum Soo Kim Tae-Hwan Kim Ghil Suk Yoon Tae Gyun Kwon See Hyung Kim |
| author_sort | Jae-Wook Chung |
| collection | DOAJ |
| description | Purpose We prospectively compared the diagnostic accuracy of kidney dynamic computed tomography (KDCT), magnetic resonance imaging (MRI), and contrast-enhanced ultrasonography (CEUS) for the assessment of small renal mass (SRM) (≤4 cm). Materials and Methods Seventy-six patients with SRM (mean age, 58.4±13.1 years) who underwent renal biopsy (n=11) or nephrectomy (partial or radical) (n=65) were enrolled. All patients underwent KDCT, MRI, and CEUS before renal biopsy or nephrectomy. Results The mean maximal tumor size was 21.0±9.8 mm. The mean R.E.N.A.L nephrometry score was 7.0±1.7. Fifty-six patients had renal cell carcinoma (RCC) (clear cell, 42; papillary, 7; chromophobe, 5; succinate dehydrogenase deficient, 1; unspecified RCC, 1). Twenty patients had a benign tumor (angiomyolipoma, 11; oncocytoma, 3; others, 6). Clinicopathologic variables were comparable in RCC and benign groups. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of KDCT were 89.3%, 10.0%, 73.5%, and 25.0%, respectively. The sensitivity, specificity, PPV, and NPV of MRI were 89.3%, 10.0%, 73.5%, and 25.0%, respectively. The sensitivity, specificity, PPV, and NPV of CEUS were 85.7%, 50.0%, 82.8%, and 55.6%, respectively. The diagnostic accuracy of KDCT, MRI, and CEUS were 68.4%, 68.4%, and 76.3%, respectively. In a subgroup analysis based on clinical tumor size of 10 mm and 20 mm, CEUS also showed the highest diagnostic accuracy. Conclusions CEUS had the highest specificity, PPV, and NPV and may help improve the assessment of SRM. |
| format | Article |
| id | doaj-art-06b2bc8d2ec24920b250b6ac924c8001 |
| institution | DOAJ |
| issn | 2951-603X 2982-7043 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Korean Urological Oncology Society |
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| series | Journal of Urologic Oncology |
| spelling | doaj-art-06b2bc8d2ec24920b250b6ac924c80012025-08-20T02:51:31ZengKorean Urological Oncology SocietyJournal of Urologic Oncology2951-603X2982-70432024-07-0122212813510.22465/juo.244800320016581Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective StudyJae-Wook Chung0Seo Young Park1Seunghee Woo2Yun Ah Kim3Jun-Koo Kang4Yun-Sok Ha5Jun Nyung Lee6Bum Soo Kim7Tae-Hwan Kim8Ghil Suk Yoon9Tae Gyun Kwon10See Hyung Kim11 Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Radiology, School of Medicine, Kyungpook National University, Daegu, Korea Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Pathology, School of Medicine, Kyungpook National University, Daegu, Korea Department of Urology, Kyungpook National University Hospital, Daegu, Korea Department of Radiology, School of Medicine, Kyungpook National University, Daegu, KoreaPurpose We prospectively compared the diagnostic accuracy of kidney dynamic computed tomography (KDCT), magnetic resonance imaging (MRI), and contrast-enhanced ultrasonography (CEUS) for the assessment of small renal mass (SRM) (≤4 cm). Materials and Methods Seventy-six patients with SRM (mean age, 58.4±13.1 years) who underwent renal biopsy (n=11) or nephrectomy (partial or radical) (n=65) were enrolled. All patients underwent KDCT, MRI, and CEUS before renal biopsy or nephrectomy. Results The mean maximal tumor size was 21.0±9.8 mm. The mean R.E.N.A.L nephrometry score was 7.0±1.7. Fifty-six patients had renal cell carcinoma (RCC) (clear cell, 42; papillary, 7; chromophobe, 5; succinate dehydrogenase deficient, 1; unspecified RCC, 1). Twenty patients had a benign tumor (angiomyolipoma, 11; oncocytoma, 3; others, 6). Clinicopathologic variables were comparable in RCC and benign groups. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of KDCT were 89.3%, 10.0%, 73.5%, and 25.0%, respectively. The sensitivity, specificity, PPV, and NPV of MRI were 89.3%, 10.0%, 73.5%, and 25.0%, respectively. The sensitivity, specificity, PPV, and NPV of CEUS were 85.7%, 50.0%, 82.8%, and 55.6%, respectively. The diagnostic accuracy of KDCT, MRI, and CEUS were 68.4%, 68.4%, and 76.3%, respectively. In a subgroup analysis based on clinical tumor size of 10 mm and 20 mm, CEUS also showed the highest diagnostic accuracy. Conclusions CEUS had the highest specificity, PPV, and NPV and may help improve the assessment of SRM.http://www.e-juo.org/upload/pdf/juo-244800320016.pdfsmall renal masscomputed tomographymagnetic resonance imagingcontrast-enhanced ultrasonography |
| spellingShingle | Jae-Wook Chung Seo Young Park Seunghee Woo Yun Ah Kim Jun-Koo Kang Yun-Sok Ha Jun Nyung Lee Bum Soo Kim Tae-Hwan Kim Ghil Suk Yoon Tae Gyun Kwon See Hyung Kim Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective Study Journal of Urologic Oncology small renal mass computed tomography magnetic resonance imaging contrast-enhanced ultrasonography |
| title | Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective Study |
| title_full | Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective Study |
| title_fullStr | Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective Study |
| title_full_unstemmed | Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective Study |
| title_short | Diagnostic Accuracy of Contrast-Enhanced Ultrasonography for the Assessment of Small Renal Mass: A Prospective Study |
| title_sort | diagnostic accuracy of contrast enhanced ultrasonography for the assessment of small renal mass a prospective study |
| topic | small renal mass computed tomography magnetic resonance imaging contrast-enhanced ultrasonography |
| url | http://www.e-juo.org/upload/pdf/juo-244800320016.pdf |
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