Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review
Diabetic macular edema (DME) is the most common cause of vision loss in diabetic patients. Thirty years ago, the Early Treatment Diabetic Retinopathy Study (ETDRS) demonstrated that focal/grid laser photocoagulation reduces moderate vision loss from DME by 50% or more; thus, macular photocoagulation...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/2407037 |
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| author | Laura N. Distefano Jose Garcia-Arumi Vicente Martinez-Castillo Anna Boixadera |
| author_facet | Laura N. Distefano Jose Garcia-Arumi Vicente Martinez-Castillo Anna Boixadera |
| author_sort | Laura N. Distefano |
| collection | DOAJ |
| description | Diabetic macular edema (DME) is the most common cause of vision loss in diabetic patients. Thirty years ago, the Early Treatment Diabetic Retinopathy Study (ETDRS) demonstrated that focal/grid laser photocoagulation reduces moderate vision loss from DME by 50% or more; thus, macular photocoagulation became the gold standard treatment for DME. However, with the development of anti-VEGF drugs (bevacizumab, ranibizumab, and aflibercept), better outcomes were obtained in terms of visual acuity gain and decrease in macular thickness in some studies when antiangiogenic drugs were administered in monotherapy. Macular laser therapy may still play an important role as an adjuvant treatment because it is able to improve macular thickness outcomes and reduce the number of injections needed. Here, we review some of the clinical trials that have assessed the efficacy of macular laser treatment, either as part of the treatment protocol or as rescue therapy. |
| format | Article |
| id | doaj-art-06a12b02146440cfae10b02f221ca3cb |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-06a12b02146440cfae10b02f221ca3cb2025-02-03T06:08:01ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/24070372407037Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A ReviewLaura N. Distefano0Jose Garcia-Arumi1Vicente Martinez-Castillo2Anna Boixadera3Vall d’Hebron Hospital, Pg de la Vall d’Hebron 119, 08032 Barcelona, SpainVall d’Hebron Hospital, Pg de la Vall d’Hebron 119, 08032 Barcelona, SpainVall d’Hebron Hospital, Pg de la Vall d’Hebron 119, 08032 Barcelona, SpainVall d’Hebron Hospital, Pg de la Vall d’Hebron 119, 08032 Barcelona, SpainDiabetic macular edema (DME) is the most common cause of vision loss in diabetic patients. Thirty years ago, the Early Treatment Diabetic Retinopathy Study (ETDRS) demonstrated that focal/grid laser photocoagulation reduces moderate vision loss from DME by 50% or more; thus, macular photocoagulation became the gold standard treatment for DME. However, with the development of anti-VEGF drugs (bevacizumab, ranibizumab, and aflibercept), better outcomes were obtained in terms of visual acuity gain and decrease in macular thickness in some studies when antiangiogenic drugs were administered in monotherapy. Macular laser therapy may still play an important role as an adjuvant treatment because it is able to improve macular thickness outcomes and reduce the number of injections needed. Here, we review some of the clinical trials that have assessed the efficacy of macular laser treatment, either as part of the treatment protocol or as rescue therapy.http://dx.doi.org/10.1155/2017/2407037 |
| spellingShingle | Laura N. Distefano Jose Garcia-Arumi Vicente Martinez-Castillo Anna Boixadera Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review Journal of Ophthalmology |
| title | Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review |
| title_full | Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review |
| title_fullStr | Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review |
| title_full_unstemmed | Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review |
| title_short | Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review |
| title_sort | combination of anti vegf and laser photocoagulation for diabetic macular edema a review |
| url | http://dx.doi.org/10.1155/2017/2407037 |
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