Tutorial Review for Understanding of Cholangiopathy
The biliary tree consists of intrahepatic and extrahepatic bile ducts and is lined by biliary epithelial cells (or cholangiocytes). There are also peribiliary glands around the intrahepatic large bile ducts and extrahepatic bile ducts. The biliary tree is a conduit of bile secreted by hepatocytes an...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | International Journal of Hepatology |
Online Access: | http://dx.doi.org/10.1155/2012/547840 |
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author | Yasuni Nakanuma |
author_facet | Yasuni Nakanuma |
author_sort | Yasuni Nakanuma |
collection | DOAJ |
description | The biliary tree consists of intrahepatic and extrahepatic bile ducts and is lined by biliary epithelial cells (or cholangiocytes). There are also peribiliary glands around the intrahepatic large bile ducts and extrahepatic bile ducts. The biliary tree is a conduit of bile secreted by hepatocytes and biliary epithelial cells and also of the peribiliary glands and has several physiological roles. A number of diseases affect mainly the intrahepatic and extrahepatic biliary tree, and, in this special issue, these cholangiopathies are reviewed in detail with respect to genetics, pathogenesis, and pathology. In this paper, the anatomy and physiology of the biliary tree, basic injuries to biliary epithelial cells from stress and bile duct damage, and representative cholangiopathies are briefly reviewed. |
format | Article |
id | doaj-art-06860bd6c8e44df0903000af8a13f911 |
institution | Kabale University |
issn | 2090-3448 2090-3456 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Hepatology |
spelling | doaj-art-06860bd6c8e44df0903000af8a13f9112025-02-03T07:26:07ZengWileyInternational Journal of Hepatology2090-34482090-34562012-01-01201210.1155/2012/547840547840Tutorial Review for Understanding of CholangiopathyYasuni Nakanuma0Department of Human Pathology, Kanazawa University Graduate School of Medical Science, Kanazawa 920-8640, JapanThe biliary tree consists of intrahepatic and extrahepatic bile ducts and is lined by biliary epithelial cells (or cholangiocytes). There are also peribiliary glands around the intrahepatic large bile ducts and extrahepatic bile ducts. The biliary tree is a conduit of bile secreted by hepatocytes and biliary epithelial cells and also of the peribiliary glands and has several physiological roles. A number of diseases affect mainly the intrahepatic and extrahepatic biliary tree, and, in this special issue, these cholangiopathies are reviewed in detail with respect to genetics, pathogenesis, and pathology. In this paper, the anatomy and physiology of the biliary tree, basic injuries to biliary epithelial cells from stress and bile duct damage, and representative cholangiopathies are briefly reviewed.http://dx.doi.org/10.1155/2012/547840 |
spellingShingle | Yasuni Nakanuma Tutorial Review for Understanding of Cholangiopathy International Journal of Hepatology |
title | Tutorial Review for Understanding of Cholangiopathy |
title_full | Tutorial Review for Understanding of Cholangiopathy |
title_fullStr | Tutorial Review for Understanding of Cholangiopathy |
title_full_unstemmed | Tutorial Review for Understanding of Cholangiopathy |
title_short | Tutorial Review for Understanding of Cholangiopathy |
title_sort | tutorial review for understanding of cholangiopathy |
url | http://dx.doi.org/10.1155/2012/547840 |
work_keys_str_mv | AT yasuninakanuma tutorialreviewforunderstandingofcholangiopathy |