Tutorial Review for Understanding of Cholangiopathy

The biliary tree consists of intrahepatic and extrahepatic bile ducts and is lined by biliary epithelial cells (or cholangiocytes). There are also peribiliary glands around the intrahepatic large bile ducts and extrahepatic bile ducts. The biliary tree is a conduit of bile secreted by hepatocytes an...

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Main Author: Yasuni Nakanuma
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Hepatology
Online Access:http://dx.doi.org/10.1155/2012/547840
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author Yasuni Nakanuma
author_facet Yasuni Nakanuma
author_sort Yasuni Nakanuma
collection DOAJ
description The biliary tree consists of intrahepatic and extrahepatic bile ducts and is lined by biliary epithelial cells (or cholangiocytes). There are also peribiliary glands around the intrahepatic large bile ducts and extrahepatic bile ducts. The biliary tree is a conduit of bile secreted by hepatocytes and biliary epithelial cells and also of the peribiliary glands and has several physiological roles. A number of diseases affect mainly the intrahepatic and extrahepatic biliary tree, and, in this special issue, these cholangiopathies are reviewed in detail with respect to genetics, pathogenesis, and pathology. In this paper, the anatomy and physiology of the biliary tree, basic injuries to biliary epithelial cells from stress and bile duct damage, and representative cholangiopathies are briefly reviewed.
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institution Kabale University
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spelling doaj-art-06860bd6c8e44df0903000af8a13f9112025-02-03T07:26:07ZengWileyInternational Journal of Hepatology2090-34482090-34562012-01-01201210.1155/2012/547840547840Tutorial Review for Understanding of CholangiopathyYasuni Nakanuma0Department of Human Pathology, Kanazawa University Graduate School of Medical Science, Kanazawa 920-8640, JapanThe biliary tree consists of intrahepatic and extrahepatic bile ducts and is lined by biliary epithelial cells (or cholangiocytes). There are also peribiliary glands around the intrahepatic large bile ducts and extrahepatic bile ducts. The biliary tree is a conduit of bile secreted by hepatocytes and biliary epithelial cells and also of the peribiliary glands and has several physiological roles. A number of diseases affect mainly the intrahepatic and extrahepatic biliary tree, and, in this special issue, these cholangiopathies are reviewed in detail with respect to genetics, pathogenesis, and pathology. In this paper, the anatomy and physiology of the biliary tree, basic injuries to biliary epithelial cells from stress and bile duct damage, and representative cholangiopathies are briefly reviewed.http://dx.doi.org/10.1155/2012/547840
spellingShingle Yasuni Nakanuma
Tutorial Review for Understanding of Cholangiopathy
International Journal of Hepatology
title Tutorial Review for Understanding of Cholangiopathy
title_full Tutorial Review for Understanding of Cholangiopathy
title_fullStr Tutorial Review for Understanding of Cholangiopathy
title_full_unstemmed Tutorial Review for Understanding of Cholangiopathy
title_short Tutorial Review for Understanding of Cholangiopathy
title_sort tutorial review for understanding of cholangiopathy
url http://dx.doi.org/10.1155/2012/547840
work_keys_str_mv AT yasuninakanuma tutorialreviewforunderstandingofcholangiopathy