Atrial Arrhythmias in Patients with Severe COVID-19
The number of confirmed COVID-19 cases has increased drastically; however, information regarding the impact of this disease on the occurrence of arrhythmias is scarce. The aim of this study was to determine the impact of COVID-19 on arrhythmia occurrence. This prospective study included patients wit...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2021/8874450 |
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| author | Kai-Yue Han Qi Qiao Ye-Qian Zhu Xin-Guang Chen Xing-Xing Kang Gao-Feng Zhang Xun-Chao Cai Yong Du Jing Jin Ruo-Min Di Chen-Xi Yang Feng-Xiang Zhang Ying-Jia Xu |
| author_facet | Kai-Yue Han Qi Qiao Ye-Qian Zhu Xin-Guang Chen Xing-Xing Kang Gao-Feng Zhang Xun-Chao Cai Yong Du Jing Jin Ruo-Min Di Chen-Xi Yang Feng-Xiang Zhang Ying-Jia Xu |
| author_sort | Kai-Yue Han |
| collection | DOAJ |
| description | The number of confirmed COVID-19 cases has increased drastically; however, information regarding the impact of this disease on the occurrence of arrhythmias is scarce. The aim of this study was to determine the impact of COVID-19 on arrhythmia occurrence. This prospective study included patients with COVID-19 treated at the Leishenshan Temporary Hospital of Wuhan City, China, from February 24 to April 5, 2020. Demographic, comorbidity, and arrhythmias data were collected from patients with COVID-19 (n = 84) and compared with control data from patients with bacterial pneumonia (n = 84) infection. Furthermore, comparisons were made between patients with severe and nonsevere COVID-19 and between older and younger patients. Compared with patients with bacterial pneumonia, those with COVID-19 had higher total, mean, and minimum heart rates (all P<0.01). Patients with severe COVID-19 (severe and critical type diseases) developed more atrial arrhythmias compared with those with nonsevere symptoms. Plasma creatine kinase isoenzyme (CKMB) levels (P=0.01) were higher in the severe group than in the nonsevere group, and there were more deaths in the severe group than in the nonsevere group (6 (15%) vs. 3 (2.30%); P=0.05). Premature atrial contractions (PAC) and nonsustained atrial tachycardia (NSAT) were significantly positively correlated with plasma CKMB levels but not with high-sensitive cardiac troponin I or myoglobin levels. Our data demonstrate that COVID-19 patients have higher total, mean, and minimum heart rates compared with those with bacterial pneumonia. Patients with severe or critical disease had more frequent atrial arrhythmias (including PAC and AF) and higher CKMB levels and mortality than those with nonsevere symptoms. |
| format | Article |
| id | doaj-art-067d880085a14598b397d47b3717fdc4 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-067d880085a14598b397d47b3717fdc42025-02-03T06:07:39ZengWileyCardiology Research and Practice2090-80162090-05972021-01-01202110.1155/2021/88744508874450Atrial Arrhythmias in Patients with Severe COVID-19Kai-Yue Han0Qi Qiao1Ye-Qian Zhu2Xin-Guang Chen3Xing-Xing Kang4Gao-Feng Zhang5Xun-Chao Cai6Yong Du7Jing Jin8Ruo-Min Di9Chen-Xi Yang10Feng-Xiang Zhang11Ying-Jia Xu12Department of Cardiology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, ChinaDepartment of Cardiology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, ChinaDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, ChinaDepartment of Bioinformatics, School of Medical Informatics and Engineering, Xuzhou Medical University, Xuzhou, ChinaDepartment of Cardiology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, ChinaCollege of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, ChinaDepartment of Cardiology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, ChinaDepartment of Cardiology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, ChinaDepartment of Cardiology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, ChinaDepartment of Cardiology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, ChinaDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, ChinaThe number of confirmed COVID-19 cases has increased drastically; however, information regarding the impact of this disease on the occurrence of arrhythmias is scarce. The aim of this study was to determine the impact of COVID-19 on arrhythmia occurrence. This prospective study included patients with COVID-19 treated at the Leishenshan Temporary Hospital of Wuhan City, China, from February 24 to April 5, 2020. Demographic, comorbidity, and arrhythmias data were collected from patients with COVID-19 (n = 84) and compared with control data from patients with bacterial pneumonia (n = 84) infection. Furthermore, comparisons were made between patients with severe and nonsevere COVID-19 and between older and younger patients. Compared with patients with bacterial pneumonia, those with COVID-19 had higher total, mean, and minimum heart rates (all P<0.01). Patients with severe COVID-19 (severe and critical type diseases) developed more atrial arrhythmias compared with those with nonsevere symptoms. Plasma creatine kinase isoenzyme (CKMB) levels (P=0.01) were higher in the severe group than in the nonsevere group, and there were more deaths in the severe group than in the nonsevere group (6 (15%) vs. 3 (2.30%); P=0.05). Premature atrial contractions (PAC) and nonsustained atrial tachycardia (NSAT) were significantly positively correlated with plasma CKMB levels but not with high-sensitive cardiac troponin I or myoglobin levels. Our data demonstrate that COVID-19 patients have higher total, mean, and minimum heart rates compared with those with bacterial pneumonia. Patients with severe or critical disease had more frequent atrial arrhythmias (including PAC and AF) and higher CKMB levels and mortality than those with nonsevere symptoms.http://dx.doi.org/10.1155/2021/8874450 |
| spellingShingle | Kai-Yue Han Qi Qiao Ye-Qian Zhu Xin-Guang Chen Xing-Xing Kang Gao-Feng Zhang Xun-Chao Cai Yong Du Jing Jin Ruo-Min Di Chen-Xi Yang Feng-Xiang Zhang Ying-Jia Xu Atrial Arrhythmias in Patients with Severe COVID-19 Cardiology Research and Practice |
| title | Atrial Arrhythmias in Patients with Severe COVID-19 |
| title_full | Atrial Arrhythmias in Patients with Severe COVID-19 |
| title_fullStr | Atrial Arrhythmias in Patients with Severe COVID-19 |
| title_full_unstemmed | Atrial Arrhythmias in Patients with Severe COVID-19 |
| title_short | Atrial Arrhythmias in Patients with Severe COVID-19 |
| title_sort | atrial arrhythmias in patients with severe covid 19 |
| url | http://dx.doi.org/10.1155/2021/8874450 |
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