Nickel-catalyzed cross-coupling of 2-fluorobenzofurans with arylboronic acids via aromatic C–F bond activation

Nickel-catalyzed cross-coupling of 2-fluorobenzofurans with arylboronic acids via aromatic C–F bond activation

2-Fluorobenzofurans underwent efficient nickel-catalyzed coupling with arylboronic acids through the activation of aromatic C–F bonds. This method allowed us to successfully synthesize a range of 2-arylbenzofurans with various substituents. The reaction, which proceeded under mild conditions, involv...

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Bibliographic Details
Main Authors: Takeshi Fujita, Haruna Yabuki, Ryutaro Morioka, Kohei Fuchibe, Junji Ichikawa
Format: Article
Language:English
Published: Beilstein-Institut 2025-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
arylboronic acid
benzofuran
c–f bond activation
cross-coupling
nickel
Online Access:https://doi.org/10.3762/bjoc.21.8
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