PPARγ Ligands Regulate Noncontractile and Contractile Functions of Airway Smooth Muscle: Implications for Asthma Therapy
In asthma, the increase in airway smooth muscle (ASM) can contribute to inflammation, airway wall remodeling and airway hyperresponsiveness (AHR). Targetting peroxisome proliferator-activated receptor γ (PPARγ), a receptor upregulated in ASM in asthmatic airways, may provide a novel approach to regu...
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Main Authors: | Chantal Donovan, Xiahui Tan, Jane Elizabeth Bourke |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2012/809164 |
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