Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosis

Peritoneal dialysis is one of renal replacement therapies for patients with end-stage renal disease(ESRD).Peritoneal dialysis-related peritoneal fibrosis is the most important reason for withdrawing peritoneal dialysis in ESRD patients.Previous studies have hinted that a major mechanism of peritonea...

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Main Authors: Liao Meng, Chen Si-jie, Tang Ri-ning, Zhang Xiao-liang
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2021-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/thesisDetails?columnId=57903532&Fpath=home&index=0
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author Liao Meng
Chen Si-jie
Tang Ri-ning
Zhang Xiao-liang
author_facet Liao Meng
Chen Si-jie
Tang Ri-ning
Zhang Xiao-liang
author_sort Liao Meng
collection DOAJ
description Peritoneal dialysis is one of renal replacement therapies for patients with end-stage renal disease(ESRD).Peritoneal dialysis-related peritoneal fibrosis is the most important reason for withdrawing peritoneal dialysis in ESRD patients.Previous studies have hinted that a major mechanism of peritoneal fibrosis is epithelial-mesenchymal transition(EMT).Recentstudies have found that endothelial-mesenchymal transition(EndMT)may be one of the mechanisms of peritoneal fibrosis.High glucose, inflammation and oxidative stress affect the occurrence and development of EndMT in peritoneal tissues.This review summarized the latest advances of EndMTduring peritoneal dialysis-related peritoneal fibrosis.
format Article
id doaj-art-05f011dea7f9445a80d11b149d6404b6
institution OA Journals
issn 1671-2390
language zho
publishDate 2021-01-01
publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-05f011dea7f9445a80d11b149d6404b62025-08-20T02:16:13ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-0184885557903532Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosisLiao MengChen Si-jieTang Ri-ningZhang Xiao-liangPeritoneal dialysis is one of renal replacement therapies for patients with end-stage renal disease(ESRD).Peritoneal dialysis-related peritoneal fibrosis is the most important reason for withdrawing peritoneal dialysis in ESRD patients.Previous studies have hinted that a major mechanism of peritoneal fibrosis is epithelial-mesenchymal transition(EMT).Recentstudies have found that endothelial-mesenchymal transition(EndMT)may be one of the mechanisms of peritoneal fibrosis.High glucose, inflammation and oxidative stress affect the occurrence and development of EndMT in peritoneal tissues.This review summarized the latest advances of EndMTduring peritoneal dialysis-related peritoneal fibrosis.http://www.lcszb.com/thesisDetails?columnId=57903532&Fpath=home&index=0Endothelial-mesenchymal transitionPeritoneal fibrosisPeritoneal dialysis
spellingShingle Liao Meng
Chen Si-jie
Tang Ri-ning
Zhang Xiao-liang
Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosis
Linchuang shenzangbing zazhi
Endothelial-mesenchymal transition
Peritoneal fibrosis
Peritoneal dialysis
title Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosis
title_full Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosis
title_fullStr Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosis
title_full_unstemmed Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosis
title_short Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosis
title_sort research advances of endothelial mesenchymal transition during peritoneal dialysis related peritoneal fibrosis
topic Endothelial-mesenchymal transition
Peritoneal fibrosis
Peritoneal dialysis
url http://www.lcszb.com/thesisDetails?columnId=57903532&Fpath=home&index=0
work_keys_str_mv AT liaomeng researchadvancesofendothelialmesenchymaltransitionduringperitonealdialysisrelatedperitonealfibrosis
AT chensijie researchadvancesofendothelialmesenchymaltransitionduringperitonealdialysisrelatedperitonealfibrosis
AT tangrining researchadvancesofendothelialmesenchymaltransitionduringperitonealdialysisrelatedperitonealfibrosis
AT zhangxiaoliang researchadvancesofendothelialmesenchymaltransitionduringperitonealdialysisrelatedperitonealfibrosis