Predictive capabilities of polygenic scores in an East-Asian population-based cohort: the Singapore Chinese health study

Predictive capabilities of polygenic scores in an East-Asian population-based cohort: the Singapore Chinese health study

Abstract Polygenic scores (PGS) are derived primarily from European population studies. It is unclear how these perform in risk predictions among East-Asians. We generated 2173 PGSs from 519 traits and assessed their associations with 58 baseline phenotypes in the Singapore Chinese Health Study, a p...

Full description

Saved in:
Bibliographic Details
Main Authors: Xuling Chang, Chih Chuan Shih, Jieqi Chen, Ai Shan Lee, Patrick Tan, Ling Wang, Jianjun Liu, Jingmei Li, Jian-Min Yuan, Chiea Chuen Khor, Woon-Puay Koh, Rajkumar Dorajoo
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08675-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items