Impact of vancomycin area under the curve in early or later phase on efficacy and nephrotoxicity in patients with enterococcal bloodstream infections: a multicenter study

Impact of vancomycin area under the curve in early or later phase on efficacy and nephrotoxicity in patients with enterococcal bloodstream infections: a multicenter study

Abstract Background The optimal pharmacokinetic and pharmacodynamic (PK/PD) parameters of vancomycin that can improve outcomes in enterococcal infections remain controversial. To clarify the therapeutic target for this antibiotic, this study aimed to determine vancomycin PK/PD parameters associated...

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Bibliographic Details
Main Authors: Piyawadee Tangvichitrerk, Dhitiwat Changpradub, Jatapat Hemapanpairoa, Piraporn Juntanawiwat, Wichai Santimaleeworagun
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Infectious Diseases
Subjects:
Acute kidney injury
Enterococci
Glycopeptide
PK/PD target
Therapeutic drug monitoring
Online Access:https://doi.org/10.1186/s12879-024-10399-9
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