Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line

Overexpression of efflux transporters, in human cells, is a mechanism of resistance to drug and also to chemotherapy. We found that multidrug resistance protein-4 (MRP4) overexpression has a role in reducing aspirin action in patients after bypass surgery and, very recently, we found that aspirin en...

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Bibliographic Details
Main Authors: Isabella Massimi, Ambra Ciuffetta, Flavia Temperilli, Francesca Ferrandino, Alessandra Zicari, Fabio M. Pulcinelli, Maria Pia Felli
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/607957
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