LncRNA LYPLAL1, miR-204-5p, and SIRT1: novel signatures for risk assessment of diabetic macrovascular complications

LncRNA LYPLAL1, miR-204-5p, and SIRT1: novel signatures for risk assessment of diabetic macrovascular complications

Abstract Long-term, uncontrolled diabetes mellitus can lead to micro- and macrovascular problems. The protective function of lncRNA LYPLAL1 is to reduce endothelium cell inflammation by upregulating sirtuin 1 (SIRT1) and reducing microRNA (miR)-204-5p. This work attempted to examine the lncRNA LYPLA...

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Main Authors: Maysa A. Mobasher, Marwa A. Shabana, Mousa O. Germoush, Najlaa Yousef Abuzinadah, Amir Abd-elhameed, Shereen A. Baioumy, Moataz A. ElKot, Marwa M. Esawy
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
LncRNA LYPLAL1
MiR-204-5p
SIRT1
Diabetes
Macrovascular complications
Online Access:https://doi.org/10.1038/s41598-024-75543-6
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https://doi.org/10.1038/s41598-024-75543-6

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