Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe
For full HIV virological suppression, three fully active antiretroviral agents are required. New drug classes should be included to ensure that agents are fully active. The addition of enfuvirtide and efavirenz to the present patient’s new antiretroviral regimen ensured that two fully active agents...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2007/423578 |
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| _version_ | 1832546712543035392 |
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| author | Mona Loutfy Colin Kovacs |
| author_facet | Mona Loutfy Colin Kovacs |
| author_sort | Mona Loutfy |
| collection | DOAJ |
| description | For full HIV virological suppression, three fully active antiretroviral agents are required. New drug classes should be included to ensure that agents are fully active. The addition of enfuvirtide and efavirenz to the present patient’s new antiretroviral regimen ensured that two fully active agents were in use in the setting of a moderate degree of nucleoside resistance and a high level of protease resistance, and where non-nucleoside reverse transcriptase inhibitors were still fully active. Both viral load and CD4 count responded favourably to this regimen. The patient received support from physicians and clinic staff in the introduction and use of enfuvirtide. To reduce injection site reactions, a needle-free injection system (Biojector) proved effective. |
| format | Article |
| id | doaj-art-05b9d6b7e411417db8bfbd791f5b9849 |
| institution | Kabale University |
| issn | 1712-9532 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-05b9d6b7e411417db8bfbd791f5b98492025-02-03T06:47:23ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322007-01-0118Suppl A10A11A10.1155/2007/423578Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and SafeMona Loutfy0Colin Kovacs1Division of Infectious Diseases, University of Toronto and Maple Leaf Medical Clinic, Toronto, Ontario, CanadaDivision of Infectious Diseases, University of Toronto and Maple Leaf Medical Clinic, Toronto, Ontario, CanadaFor full HIV virological suppression, three fully active antiretroviral agents are required. New drug classes should be included to ensure that agents are fully active. The addition of enfuvirtide and efavirenz to the present patient’s new antiretroviral regimen ensured that two fully active agents were in use in the setting of a moderate degree of nucleoside resistance and a high level of protease resistance, and where non-nucleoside reverse transcriptase inhibitors were still fully active. Both viral load and CD4 count responded favourably to this regimen. The patient received support from physicians and clinic staff in the introduction and use of enfuvirtide. To reduce injection site reactions, a needle-free injection system (Biojector) proved effective.http://dx.doi.org/10.1155/2007/423578 |
| spellingShingle | Mona Loutfy Colin Kovacs Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe |
| title_full | Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe |
| title_fullStr | Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe |
| title_full_unstemmed | Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe |
| title_short | Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe |
| title_sort | triple active antiretroviral regimen including enfuvirtide via the biojector is effective and safe |
| url | http://dx.doi.org/10.1155/2007/423578 |
| work_keys_str_mv | AT monaloutfy tripleactiveantiretroviralregimenincludingenfuvirtideviathebiojectoriseffectiveandsafe AT colinkovacs tripleactiveantiretroviralregimenincludingenfuvirtideviathebiojectoriseffectiveandsafe |