Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS
Although the prospects for successful treatment of Mycobacterium avium complex (MAC) infection in AIDS recently seemed quite dismal, the introduction of the semisynthetic macrolides, clarithromycin and azithromycin, has altered this perspective. Several recent clinical studies have been key to our u...
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| Format: | Article |
| Language: | English |
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Wiley
1994-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1994/549025 |
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| _version_ | 1832560226194161664 |
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| author | Carol A Kemper |
| author_facet | Carol A Kemper |
| author_sort | Carol A Kemper |
| collection | DOAJ |
| description | Although the prospects for successful treatment of Mycobacterium avium complex (MAC) infection in AIDS recently seemed quite dismal, the introduction of
the semisynthetic macrolides, clarithromycin and azithromycin, has altered this perspective. Several recent clinical studies have been key to our understanding of the successful management of these patients and are the basis of this review. Yet, some patients with disseminated MAC remain poorly responsive to therapy, intolerance often limits therapy, and recrudescent bacteremia often occurs. Though our understanding of this infection has been rapidly advanced in the past three years. much remains to be learned about its optimal therapeutic management. |
| format | Article |
| id | doaj-art-05b729a43cfa42b2a71d4188149f9013 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1994-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-05b729a43cfa42b2a71d4188149f90132025-02-03T01:28:01ZengWileyCanadian Journal of Infectious Diseases1180-23321994-01-015Suppl B14B20B10.1155/1994/549025Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDSCarol A Kemper0Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, San Jose, USAAlthough the prospects for successful treatment of Mycobacterium avium complex (MAC) infection in AIDS recently seemed quite dismal, the introduction of the semisynthetic macrolides, clarithromycin and azithromycin, has altered this perspective. Several recent clinical studies have been key to our understanding of the successful management of these patients and are the basis of this review. Yet, some patients with disseminated MAC remain poorly responsive to therapy, intolerance often limits therapy, and recrudescent bacteremia often occurs. Though our understanding of this infection has been rapidly advanced in the past three years. much remains to be learned about its optimal therapeutic management.http://dx.doi.org/10.1155/1994/549025 |
| spellingShingle | Carol A Kemper Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS Canadian Journal of Infectious Diseases |
| title | Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS |
| title_full | Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS |
| title_fullStr | Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS |
| title_full_unstemmed | Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS |
| title_short | Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS |
| title_sort | advances in the treatment of desseminated mycobacterium avium complex in adults with aids |
| url | http://dx.doi.org/10.1155/1994/549025 |
| work_keys_str_mv | AT carolakemper advancesinthetreatmentofdesseminatedmycobacteriumaviumcomplexinadultswithaids |