Unexpected Convergence: A Case Report of Achalasia in a Patient With Multiple Sclerosis
Achalasia is an esophageal motility disorder marked by neuronal degeneration within the myenteric plexus, leading to impaired lower esophageal relaxation and swallowing dysfunction. Despite a detailed understanding of its features, the disease's cause remains unknown. Similarly, multiple sclero...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2025-01-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0580 |
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| author | Saeed S. Graham Adrianna E. Carrasco Jinye Liu Mohamed Khalaf William J. Leland |
| author_facet | Saeed S. Graham Adrianna E. Carrasco Jinye Liu Mohamed Khalaf William J. Leland |
| author_sort | Saeed S. Graham |
| collection | DOAJ |
| description | Achalasia is an esophageal motility disorder marked by neuronal degeneration within the myenteric plexus, leading to impaired lower esophageal relaxation and swallowing dysfunction. Despite a detailed understanding of its features, the disease's cause remains unknown. Similarly, multiple sclerosis (MS) is an inflammatory demyelinating condition of uncertain cause. Autoimmunity has been suggested as a potential cause of both disorders, yet instances documenting their co-occurrence are rare. We report a case of achalasia diagnosed in a young woman during hospitalization for an apparent MS flare. |
| format | Article |
| id | doaj-art-059ec6cb771244bba9f67cf6350c0e34 |
| institution | OA Journals |
| issn | 2767-7664 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-059ec6cb771244bba9f67cf6350c0e342025-08-20T02:11:54ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642025-01-014110.7326/aimcc.2024.0580Unexpected Convergence: A Case Report of Achalasia in a Patient With Multiple SclerosisSaeed S. Graham0Adrianna E. Carrasco1Jinye Liu2Mohamed Khalaf3William J. Leland41Department of Internal Medicine, East Carolina University Brody School of Medicine, Greenville, North Carolina2Department of Neurology, University of California, Los Angeles, Los Angeles, California1Department of Internal Medicine, East Carolina University Brody School of Medicine, Greenville, North Carolina3Department of Gastroenterology and Hepatology, East Carolina University Brody School of Medicine, Greenville, North Carolina3Department of Gastroenterology and Hepatology, East Carolina University Brody School of Medicine, Greenville, North CarolinaAchalasia is an esophageal motility disorder marked by neuronal degeneration within the myenteric plexus, leading to impaired lower esophageal relaxation and swallowing dysfunction. Despite a detailed understanding of its features, the disease's cause remains unknown. Similarly, multiple sclerosis (MS) is an inflammatory demyelinating condition of uncertain cause. Autoimmunity has been suggested as a potential cause of both disorders, yet instances documenting their co-occurrence are rare. We report a case of achalasia diagnosed in a young woman during hospitalization for an apparent MS flare.https://www.acpjournals.org/doi/10.7326/aimcc.2024.0580 |
| spellingShingle | Saeed S. Graham Adrianna E. Carrasco Jinye Liu Mohamed Khalaf William J. Leland Unexpected Convergence: A Case Report of Achalasia in a Patient With Multiple Sclerosis Annals of Internal Medicine: Clinical Cases |
| title | Unexpected Convergence: A Case Report of Achalasia in a Patient With Multiple Sclerosis |
| title_full | Unexpected Convergence: A Case Report of Achalasia in a Patient With Multiple Sclerosis |
| title_fullStr | Unexpected Convergence: A Case Report of Achalasia in a Patient With Multiple Sclerosis |
| title_full_unstemmed | Unexpected Convergence: A Case Report of Achalasia in a Patient With Multiple Sclerosis |
| title_short | Unexpected Convergence: A Case Report of Achalasia in a Patient With Multiple Sclerosis |
| title_sort | unexpected convergence a case report of achalasia in a patient with multiple sclerosis |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0580 |
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