SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?

Introduction. In developing countries, a lack of decentralization of perinatal care leads to many high-risk births occurring in facilities that do not have NICU, leading to admission to a PICU. Objective. To assess SNAP II and SNAPPE II as predictors of neonatal death in the PICU. Methodology. A pro...

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Main Authors: Mirta Noemi Mesquita Ramirez, Laura Evangelina Godoy, Elizabeth Alvarez Barrientos
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Pediatrics
Online Access:http://dx.doi.org/10.1155/2014/298198
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author Mirta Noemi Mesquita Ramirez
Laura Evangelina Godoy
Elizabeth Alvarez Barrientos
author_facet Mirta Noemi Mesquita Ramirez
Laura Evangelina Godoy
Elizabeth Alvarez Barrientos
author_sort Mirta Noemi Mesquita Ramirez
collection DOAJ
description Introduction. In developing countries, a lack of decentralization of perinatal care leads to many high-risk births occurring in facilities that do not have NICU, leading to admission to a PICU. Objective. To assess SNAP II and SNAPPE II as predictors of neonatal death in the PICU. Methodology. A prospective study of newborns divided into 3 groups according to postnatal age: Group 1 (G1), of 0 to 6 days; Group 2 (G2) of 7 to 14 days; and Group 3 (G3), of 15 to 28 days. Variables analyzed were SNAP II, SNAPPE II, perinatal data, and known risk factors for death. The Hosmer-Lemeshow test and the receiver operating characteristics (ROC) curve were used with SPSS 17.0 for statistical analysis. An Alpha error <5% was considered significant. Results. We analyzed 290 newborns, including 192 from G1, 41 from G2, and 57 from G3. Mortality was similar in all 3 groups. Median SNAP II was higher in newborns that died in all 3 groups (P<0.05). The area under the ROC curve for SNAP II for G1 was 0.78 (CI 95% 0.70–0.86), for G2 0.66 (CI 95% 0.37–0.94), and for G3 0.74 (CI 95% 0.53–0.93). The area under the ROC curve for SNAPPE II for G1 was 0.76 (CI 95% 0.67–0.85), for G2 0.60 (CI 95% 0.30–0.90), and for G3 0.74 (CI 95% 0.52–0.95). Conclusions. SNAP II and SNAPPE II showed moderate discrimination in predicting mortality. The results are not strong enough to establish the correlation between the score and the risk of mortality.
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spelling doaj-art-0599b76ddb0c4de39cb4999aa06c8edd2025-02-03T01:12:09ZengWileyInternational Journal of Pediatrics1687-97401687-97592014-01-01201410.1155/2014/298198298198SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?Mirta Noemi Mesquita Ramirez0Laura Evangelina Godoy1Elizabeth Alvarez Barrientos2Hospital General Pediátrico “Niños de Acosta Ñú”, Avenida de la Victoria and Bacigalupo, Reducto, 2160 San Lorenzo, ParaguayHospital General Pediátrico “Niños de Acosta Ñú”, Avenida de la Victoria and Bacigalupo, Reducto, 2160 San Lorenzo, ParaguayHospital General Pediátrico “Niños de Acosta Ñú”, Avenida de la Victoria and Bacigalupo, Reducto, 2160 San Lorenzo, ParaguayIntroduction. In developing countries, a lack of decentralization of perinatal care leads to many high-risk births occurring in facilities that do not have NICU, leading to admission to a PICU. Objective. To assess SNAP II and SNAPPE II as predictors of neonatal death in the PICU. Methodology. A prospective study of newborns divided into 3 groups according to postnatal age: Group 1 (G1), of 0 to 6 days; Group 2 (G2) of 7 to 14 days; and Group 3 (G3), of 15 to 28 days. Variables analyzed were SNAP II, SNAPPE II, perinatal data, and known risk factors for death. The Hosmer-Lemeshow test and the receiver operating characteristics (ROC) curve were used with SPSS 17.0 for statistical analysis. An Alpha error <5% was considered significant. Results. We analyzed 290 newborns, including 192 from G1, 41 from G2, and 57 from G3. Mortality was similar in all 3 groups. Median SNAP II was higher in newborns that died in all 3 groups (P<0.05). The area under the ROC curve for SNAP II for G1 was 0.78 (CI 95% 0.70–0.86), for G2 0.66 (CI 95% 0.37–0.94), and for G3 0.74 (CI 95% 0.53–0.93). The area under the ROC curve for SNAPPE II for G1 was 0.76 (CI 95% 0.67–0.85), for G2 0.60 (CI 95% 0.30–0.90), and for G3 0.74 (CI 95% 0.52–0.95). Conclusions. SNAP II and SNAPPE II showed moderate discrimination in predicting mortality. The results are not strong enough to establish the correlation between the score and the risk of mortality.http://dx.doi.org/10.1155/2014/298198
spellingShingle Mirta Noemi Mesquita Ramirez
Laura Evangelina Godoy
Elizabeth Alvarez Barrientos
SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?
International Journal of Pediatrics
title SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?
title_full SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?
title_fullStr SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?
title_full_unstemmed SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?
title_short SNAP II and SNAPPE II as Predictors of Neonatal Mortality in a Pediatric Intensive Care Unit: Does Postnatal Age Play a Role?
title_sort snap ii and snappe ii as predictors of neonatal mortality in a pediatric intensive care unit does postnatal age play a role
url http://dx.doi.org/10.1155/2014/298198
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