Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy

Abstract Background Pediatric sedation clinics are rare in low-income countries. Our aim is to describe the establishment of the first-ever pediatric sedation clinic in Ethiopia and provide an assessment of its safety and efficacy over the 5 years since its establishment. Methods A multi-phase appro...

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Main Authors: Tigist Bacha, Segni Kejela, Scott A. Hagen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Pediatrics
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Online Access:https://doi.org/10.1186/s12887-024-05351-4
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author Tigist Bacha
Segni Kejela
Scott A. Hagen
author_facet Tigist Bacha
Segni Kejela
Scott A. Hagen
author_sort Tigist Bacha
collection DOAJ
description Abstract Background Pediatric sedation clinics are rare in low-income countries. Our aim is to describe the establishment of the first-ever pediatric sedation clinic in Ethiopia and provide an assessment of its safety and efficacy over the 5 years since its establishment. Methods A multi-phase approach was undertaken. In the first phase, we analyzed barriers to procedural pain management through repeated focus group discussions with stakeholders. Subsequently, we conducted a modified sedation provider course from the Society for Pediatric Sedation (SPS) with pre and post-training testing to document course effectiveness. Finally, we developed a procedural sedation clinic at Tikur Anbessa Specialized Hospital. In the second phase, we prospectively collected outcome data over a 5-year period from patients receiving procedural sedation at the clinic. This included assessing the efficacy of sedation and documenting any adverse events that occurred during the procedures. Result One hundred three providers completed the procedural sedation course. There was a 13.4% improvement in knowledge between baseline and post-course testing. A total of 2,820 patients underwent procedural sedation over the 5-year period from 2016 through 2021, and data selected from 475 (16.8%) patients were analyzed. The most common procedure performed was bone marrow aspiration/biopsy in 384 subjects (80.8%). The most common procedural sedation used was the combination of ketamine and propofol in 60.6%. The mean pain score during the procedure was 0.28/10, which was significantly lower than the pre-procedural pain score (p-value < 0.001). A total of 9 (1.9%) patients had adverse events and there was no mortality. Conclusion Based on our experience, development of a safe and effective sedation clinic is possible in resource-limited settings as evidenced by low procedural pain scores, and low adverse events rates. Provider training based on a modification of the SPS course improved overall procedural sedation knowledge.
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spelling doaj-art-059553ae4efb48daa138af275be3cffa2025-02-02T12:42:59ZengBMCBMC Pediatrics1471-24312025-01-012511910.1186/s12887-024-05351-4Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacyTigist Bacha0Segni Kejela1Scott A. Hagen2Department of Pediatrics and Child Health, Division of Pediatric Emergency and Critical Care, Saint Paul’s Millennium Medical CollegeCollege of Health Sciences, Department of Surgery, Addis Ababa UniversityDepartment of Pediatrics, University of WisconsinAbstract Background Pediatric sedation clinics are rare in low-income countries. Our aim is to describe the establishment of the first-ever pediatric sedation clinic in Ethiopia and provide an assessment of its safety and efficacy over the 5 years since its establishment. Methods A multi-phase approach was undertaken. In the first phase, we analyzed barriers to procedural pain management through repeated focus group discussions with stakeholders. Subsequently, we conducted a modified sedation provider course from the Society for Pediatric Sedation (SPS) with pre and post-training testing to document course effectiveness. Finally, we developed a procedural sedation clinic at Tikur Anbessa Specialized Hospital. In the second phase, we prospectively collected outcome data over a 5-year period from patients receiving procedural sedation at the clinic. This included assessing the efficacy of sedation and documenting any adverse events that occurred during the procedures. Result One hundred three providers completed the procedural sedation course. There was a 13.4% improvement in knowledge between baseline and post-course testing. A total of 2,820 patients underwent procedural sedation over the 5-year period from 2016 through 2021, and data selected from 475 (16.8%) patients were analyzed. The most common procedure performed was bone marrow aspiration/biopsy in 384 subjects (80.8%). The most common procedural sedation used was the combination of ketamine and propofol in 60.6%. The mean pain score during the procedure was 0.28/10, which was significantly lower than the pre-procedural pain score (p-value < 0.001). A total of 9 (1.9%) patients had adverse events and there was no mortality. Conclusion Based on our experience, development of a safe and effective sedation clinic is possible in resource-limited settings as evidenced by low procedural pain scores, and low adverse events rates. Provider training based on a modification of the SPS course improved overall procedural sedation knowledge.https://doi.org/10.1186/s12887-024-05351-4PediatricsProcedural sedationLow resource settingQuality improvement
spellingShingle Tigist Bacha
Segni Kejela
Scott A. Hagen
Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy
BMC Pediatrics
Pediatrics
Procedural sedation
Low resource setting
Quality improvement
title Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy
title_full Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy
title_fullStr Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy
title_full_unstemmed Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy
title_short Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy
title_sort establishing the first ever pediatric procedural sedation clinic in a low income country assessment of the safety and efficacy
topic Pediatrics
Procedural sedation
Low resource setting
Quality improvement
url https://doi.org/10.1186/s12887-024-05351-4
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AT scottahagen establishingthefirsteverpediatricproceduralsedationclinicinalowincomecountryassessmentofthesafetyandefficacy