Single-atom Pt-doped ceria nanozymes mitigate myocardial ischemia reperfusion injury via cardiomyocyte-targeted uptake and suppression of reactive oxygen species

Single-atom Pt-doped ceria nanozymes mitigate myocardial ischemia reperfusion injury via cardiomyocyte-targeted uptake and suppression of reactive oxygen species

The primary treatment for myocardial infarction (MI) is restoring blood flow to the obstructed coronary artery. However, this approach can paradoxically generate reactive oxygen species (ROS), leading to secondary ischemia-reperfusion (IR) injury. Multifunctional nanomaterials present a promising al...

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Bibliographic Details
Main Authors: Aoyang Pu, Woo-Sup Sim, Yunseong Ji, Amal George Kurian, Jung-Hwan Lee, Thi Van Anh Bui, Yimin Lai, Hyesoo Hwangbo, Huanhuan Sun, Hae-Won Kim, Hun-Jun Park, Kiwon Ban
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-11-01
Series:Bioactive Materials
Subjects:
Ceria nanozymes
Myocardial ischemia-reperfusion (IR) injury
Reactive oxygen species (ROS)
Cardiomyocyte-targeted
Antioxidation
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25003123
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