Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status

Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lympho...

Full description

Saved in:
Bibliographic Details
Main Authors: T. Jaeger, J. Ring, C. Andres
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2012/983421
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849308400446341120
author T. Jaeger
J. Ring
C. Andres
author_facet T. Jaeger
J. Ring
C. Andres
author_sort T. Jaeger
collection DOAJ
description Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical fibroxanthoma. In this review article clinical, histopathological and immunhistochemical features of Merkel cell carcinoma are reported. In addition, the role of Merkel cell polyomavirus is discussed.
format Article
id doaj-art-05639fd4fbed4ee89496e31c7a563be0
institution Kabale University
issn 2090-2905
2090-2913
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Journal of Skin Cancer
spelling doaj-art-05639fd4fbed4ee89496e31c7a563be02025-08-20T03:54:28ZengWileyJournal of Skin Cancer2090-29052090-29132012-01-01201210.1155/2012/983421983421Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus StatusT. Jaeger0J. Ring1C. Andres2Department of Dermatology and Allergy Biederstein, Technische Universität München, 80802 Munich, GermanyDepartment of Dermatology and Allergy Biederstein, Technische Universität München, 80802 Munich, GermanyDepartment of Dermatology and Allergy Biederstein, Technische Universität München, 80802 Munich, GermanyMerkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical fibroxanthoma. In this review article clinical, histopathological and immunhistochemical features of Merkel cell carcinoma are reported. In addition, the role of Merkel cell polyomavirus is discussed.http://dx.doi.org/10.1155/2012/983421
spellingShingle T. Jaeger
J. Ring
C. Andres
Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
Journal of Skin Cancer
title Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_full Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_fullStr Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_full_unstemmed Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_short Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_sort histological immunohistological and clinical features of merkel cell carcinoma in correlation to merkel cell polyomavirus status
url http://dx.doi.org/10.1155/2012/983421
work_keys_str_mv AT tjaeger histologicalimmunohistologicalandclinicalfeaturesofmerkelcellcarcinomaincorrelationtomerkelcellpolyomavirusstatus
AT jring histologicalimmunohistologicalandclinicalfeaturesofmerkelcellcarcinomaincorrelationtomerkelcellpolyomavirusstatus
AT candres histologicalimmunohistologicalandclinicalfeaturesofmerkelcellcarcinomaincorrelationtomerkelcellpolyomavirusstatus