Caco-2 Intestinal Permeability Study of Phenyltetrahydroquinolinedione Derivative – TRPA₁ Antagonist

Caco-2 Intestinal Permeability Study of Phenyltetrahydroquinolinedione Derivative – TRPA₁ Antagonist

Introduction. This work is devoted to the intestinal permeability study of 7-(2-chlorophenyl)-4-(4-methyl-1,3-thiazol-5-yl)-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione – innovative biologically active substance with TRPA1 antagonist activity. The phenyltetrahydroquinolinedione derivative is a promi...

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Bibliographic Details
Main Authors: N. V. Pyatigorskaya, A. D. Kravchenko
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2022-09-01
Series:Разработка и регистрация лекарственных средств
Subjects:
intestinal permeability
сасо-2
trpa₁
Online Access:https://www.pharmjournal.ru/jour/article/view/1301
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