Management of Hepatic Encephalopathy
Hepatic encephalopathy (HE), the neuropsychiatric presentation of liver disease, is associated with high morbidity and mortality. Reduction of plasma ammonia remains the central therapeutic strategy, but there is a need for newer novel therapies. We discuss current evidence supporting the use of int...
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Format: | Article |
Language: | English |
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Wiley
2011-01-01
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Series: | International Journal of Hepatology |
Online Access: | http://dx.doi.org/10.4061/2011/841407 |
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author | G. Wright A. Chattree R. Jalan |
author_facet | G. Wright A. Chattree R. Jalan |
author_sort | G. Wright |
collection | DOAJ |
description | Hepatic encephalopathy (HE), the neuropsychiatric presentation of liver disease, is associated with high morbidity and mortality. Reduction of plasma ammonia remains the central therapeutic strategy, but there is a need for newer novel therapies. We discuss current evidence supporting the use of interventions for both the general management of chronic HE and that necessary for more acute and advanced disease. |
format | Article |
id | doaj-art-0542af3d50ec4fb78857c878488461c2 |
institution | Kabale University |
issn | 2090-3448 2090-3456 |
language | English |
publishDate | 2011-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Hepatology |
spelling | doaj-art-0542af3d50ec4fb78857c878488461c22025-02-03T06:11:16ZengWileyInternational Journal of Hepatology2090-34482090-34562011-01-01201110.4061/2011/841407841407Management of Hepatic EncephalopathyG. Wright0A. Chattree1R. Jalan2University College London Institute of Hepatology, The Royal Free Hospital, Pond Street, London NW3 2PF, UKDepartment of Gastroenterology, King Georges Hospital, Barley Lane, Goodmayes, Ilford, Essex IG3 8YB, UKUniversity College London Institute of Hepatology, The Royal Free Hospital, Pond Street, London NW3 2PF, UKHepatic encephalopathy (HE), the neuropsychiatric presentation of liver disease, is associated with high morbidity and mortality. Reduction of plasma ammonia remains the central therapeutic strategy, but there is a need for newer novel therapies. We discuss current evidence supporting the use of interventions for both the general management of chronic HE and that necessary for more acute and advanced disease.http://dx.doi.org/10.4061/2011/841407 |
spellingShingle | G. Wright A. Chattree R. Jalan Management of Hepatic Encephalopathy International Journal of Hepatology |
title | Management of Hepatic Encephalopathy |
title_full | Management of Hepatic Encephalopathy |
title_fullStr | Management of Hepatic Encephalopathy |
title_full_unstemmed | Management of Hepatic Encephalopathy |
title_short | Management of Hepatic Encephalopathy |
title_sort | management of hepatic encephalopathy |
url | http://dx.doi.org/10.4061/2011/841407 |
work_keys_str_mv | AT gwright managementofhepaticencephalopathy AT achattree managementofhepaticencephalopathy AT rjalan managementofhepaticencephalopathy |