Mucinous Adenocarcinoma Arising in Chronic Perianal Fistula: Good Results with Neoadjuvant Chemoradiotherapy Followed by Surgery
Chronic perianal fistulas are a common clinical condition. However, their evolution to adenocarcinoma is rare. We report the case of a 48-year-old man with perianal chronic fistulas, who developed two perianal ulcerated lesions near the external orifices of the fistulas, which extended proximally as...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2014/386150 |
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| author | Marisa D. Santos Carlos Nogueira Carlos Lopes |
| author_facet | Marisa D. Santos Carlos Nogueira Carlos Lopes |
| author_sort | Marisa D. Santos |
| collection | DOAJ |
| description | Chronic perianal fistulas are a common clinical condition. However, their evolution to adenocarcinoma is rare. We report the case of a 48-year-old man with perianal chronic fistulas, who developed two perianal ulcerated lesions near the external orifices of the fistulas, which extended proximally as a pararectal tumor. No intestinal lesion was seen at endoscopic examination. Histopathological biopsy indicated mucinous adenocarcinoma. Staging was performed by pelvic magnetic resonance imaging (MRI) and thoracoabdominal CT scan. The patient underwent a laparoscopic colostomy followed by neoadjuvant chemoradiotherapy and then laparoscopic abdominoperineal resection followed by adjuvant therapy. We have seen a favorable outcome with no recurrence at 3 years of follow-up. |
| format | Article |
| id | doaj-art-04ef4c1dc4b64c4e9ffe626a4a81efb4 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-04ef4c1dc4b64c4e9ffe626a4a81efb42025-02-03T05:58:10ZengWileyCase Reports in Surgery2090-69002090-69192014-01-01201410.1155/2014/386150386150Mucinous Adenocarcinoma Arising in Chronic Perianal Fistula: Good Results with Neoadjuvant Chemoradiotherapy Followed by SurgeryMarisa D. Santos0Carlos Nogueira1Carlos Lopes2Departamento de Cirurgia, Serviço de Cirurgia Digestiva, Hospital de Santo António, Largo Professor Abel Salazar, 4099-003 Porto, PortugalDepartamento de Cirurgia, Serviço de Cirurgia Digestiva, Hospital de Santo António, Largo Professor Abel Salazar, 4099-003 Porto, PortugalDepartamento de Patologia, Serviço de Anatomia Patológica, Hospital de Santo António, Largo Professor Abel Salazar, 4099-003 Porto, PortugalChronic perianal fistulas are a common clinical condition. However, their evolution to adenocarcinoma is rare. We report the case of a 48-year-old man with perianal chronic fistulas, who developed two perianal ulcerated lesions near the external orifices of the fistulas, which extended proximally as a pararectal tumor. No intestinal lesion was seen at endoscopic examination. Histopathological biopsy indicated mucinous adenocarcinoma. Staging was performed by pelvic magnetic resonance imaging (MRI) and thoracoabdominal CT scan. The patient underwent a laparoscopic colostomy followed by neoadjuvant chemoradiotherapy and then laparoscopic abdominoperineal resection followed by adjuvant therapy. We have seen a favorable outcome with no recurrence at 3 years of follow-up.http://dx.doi.org/10.1155/2014/386150 |
| spellingShingle | Marisa D. Santos Carlos Nogueira Carlos Lopes Mucinous Adenocarcinoma Arising in Chronic Perianal Fistula: Good Results with Neoadjuvant Chemoradiotherapy Followed by Surgery Case Reports in Surgery |
| title | Mucinous Adenocarcinoma Arising in Chronic Perianal Fistula: Good Results with Neoadjuvant Chemoradiotherapy Followed by Surgery |
| title_full | Mucinous Adenocarcinoma Arising in Chronic Perianal Fistula: Good Results with Neoadjuvant Chemoradiotherapy Followed by Surgery |
| title_fullStr | Mucinous Adenocarcinoma Arising in Chronic Perianal Fistula: Good Results with Neoadjuvant Chemoradiotherapy Followed by Surgery |
| title_full_unstemmed | Mucinous Adenocarcinoma Arising in Chronic Perianal Fistula: Good Results with Neoadjuvant Chemoradiotherapy Followed by Surgery |
| title_short | Mucinous Adenocarcinoma Arising in Chronic Perianal Fistula: Good Results with Neoadjuvant Chemoradiotherapy Followed by Surgery |
| title_sort | mucinous adenocarcinoma arising in chronic perianal fistula good results with neoadjuvant chemoradiotherapy followed by surgery |
| url | http://dx.doi.org/10.1155/2014/386150 |
| work_keys_str_mv | AT marisadsantos mucinousadenocarcinomaarisinginchronicperianalfistulagoodresultswithneoadjuvantchemoradiotherapyfollowedbysurgery AT carlosnogueira mucinousadenocarcinomaarisinginchronicperianalfistulagoodresultswithneoadjuvantchemoradiotherapyfollowedbysurgery AT carloslopes mucinousadenocarcinomaarisinginchronicperianalfistulagoodresultswithneoadjuvantchemoradiotherapyfollowedbysurgery |