PPARα-Independent Arterial Smooth Muscle Relaxant Effects of PPARα Agonists

PPARα-Independent Arterial Smooth Muscle Relaxant Effects of PPARα Agonists

We sought to determine direct vascular effects of peroxisome proliferator-activated receptor alpha (PPARα) agonists using isolated mouse aortas and middle cerebral arteries (MCAs). The PPARα agonists GW7647, WY14643, and gemfibrozil acutely relaxed aortas held under isometric tension and dilated pre...

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Bibliographic Details
Main Authors:	Neerupma Silswal, Nikhil K. Parelkar, Michael J. Wacker, Mostafa Badr, Jon Andresen
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Series:	PPAR Research
Online Access:	http://dx.doi.org/10.1155/2012/302495
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