A Rare Case of Metastatic Choriocarcinoma of Lung Origin

Choriocarcinoma is part of the spectrum of gestational trophoblastic disease that occurs in women of reproductive age. Although the most common metastatic site of choriocarcinoma is the lung, primary pulmonary choriocarcinoma is rare. To diagnose primary pulmonary choriocarcinoma, the patient should...

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Main Authors: Parth Rali, Jianwu Xie, Grishma Rali, Mayur Rali, Jan Silverman, Khalid Malik
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2017/4649813
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author Parth Rali
Jianwu Xie
Grishma Rali
Mayur Rali
Jan Silverman
Khalid Malik
author_facet Parth Rali
Jianwu Xie
Grishma Rali
Mayur Rali
Jan Silverman
Khalid Malik
author_sort Parth Rali
collection DOAJ
description Choriocarcinoma is part of the spectrum of gestational trophoblastic disease that occurs in women of reproductive age. Although the most common metastatic site of choriocarcinoma is the lung, primary pulmonary choriocarcinoma is rare. To diagnose primary pulmonary choriocarcinoma, the patient should have no previous gynecologic malignancy, have elevated human chorionic gonadotropin, and have pathological confirmation of the disease excluding gonadal primary site of the tumor. Due to the paucity of data, there are no guidelines for treatment. Prognosis of this malignancy is extremely poor. We report a rare case of metastatic primary lung choriocarcinoma in a 69-year-old postmenopausal woman who was treated with combination of surgery, chemotherapy, and radiation. The patient had a good outcome and is doing well after 1-year follow-up.
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institution Kabale University
issn 2090-6846
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language English
publishDate 2017-01-01
publisher Wiley
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series Case Reports in Pulmonology
spelling doaj-art-04bc5c9ec7eb4826894e1551cd812d392025-02-03T06:00:06ZengWileyCase Reports in Pulmonology2090-68462090-68542017-01-01201710.1155/2017/46498134649813A Rare Case of Metastatic Choriocarcinoma of Lung OriginParth Rali0Jianwu Xie1Grishma Rali2Mayur Rali3Jan Silverman4Khalid Malik5Division of Pulmonary and Critical Care, Allegheny General Hospital, Pittsburgh, PA 15212, USADivision of Pathology, Allegheny General Hospital, Pittsburgh, PA 15212, USAChildren’s Hospital of Philadelphia, Philadelphia, PA, USAHofstra Northwell School of Medicine, Department of Family Medicine, Southside Hospital, Bay Shore, NY, USADivision of Pathology, Allegheny General Hospital, Pittsburgh, PA 15212, USADivision of Pulmonary and Critical Care, Allegheny General Hospital, Pittsburgh, PA 15212, USAChoriocarcinoma is part of the spectrum of gestational trophoblastic disease that occurs in women of reproductive age. Although the most common metastatic site of choriocarcinoma is the lung, primary pulmonary choriocarcinoma is rare. To diagnose primary pulmonary choriocarcinoma, the patient should have no previous gynecologic malignancy, have elevated human chorionic gonadotropin, and have pathological confirmation of the disease excluding gonadal primary site of the tumor. Due to the paucity of data, there are no guidelines for treatment. Prognosis of this malignancy is extremely poor. We report a rare case of metastatic primary lung choriocarcinoma in a 69-year-old postmenopausal woman who was treated with combination of surgery, chemotherapy, and radiation. The patient had a good outcome and is doing well after 1-year follow-up.http://dx.doi.org/10.1155/2017/4649813
spellingShingle Parth Rali
Jianwu Xie
Grishma Rali
Mayur Rali
Jan Silverman
Khalid Malik
A Rare Case of Metastatic Choriocarcinoma of Lung Origin
Case Reports in Pulmonology
title A Rare Case of Metastatic Choriocarcinoma of Lung Origin
title_full A Rare Case of Metastatic Choriocarcinoma of Lung Origin
title_fullStr A Rare Case of Metastatic Choriocarcinoma of Lung Origin
title_full_unstemmed A Rare Case of Metastatic Choriocarcinoma of Lung Origin
title_short A Rare Case of Metastatic Choriocarcinoma of Lung Origin
title_sort rare case of metastatic choriocarcinoma of lung origin
url http://dx.doi.org/10.1155/2017/4649813
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