Identification of Mutations that Encode Drug Resistance in the Polymerase Gene of the Human Immunodeficiency Virus
In vitro selection in MT-4 cells was used to generate human immunodeficiency virus-type 1 (HIV 1) variants that are resistant to 2',3'-dideoxycytidine (ddC), 2',3'-didcoxyinosine (ddI) and the (-) enantiomer of 2' ,3'-dideoxy-3'-thiacytidine (3TC). The complete rev...
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Main Authors: | Zhengxian Gu, Hengsheng Fang, Horacio Salomon, Qing Gao, Mark A Wainberg |
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Format: | Article |
Language: | English |
Published: |
Wiley
1994-01-01
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Series: | Canadian Journal of Infectious Diseases |
Online Access: | http://dx.doi.org/10.1155/1994/826340 |
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