Correlating gene expression levels with transcription factor binding sites facilitates identification of key transcription factors from transcriptome data

Correlating gene expression levels with transcription factor binding sites facilitates identification of key transcription factors from transcriptome data

Identification of key transcription factors from transcriptome data by correlating gene expression levels with transcription factor binding sites is important for transcriptome data analysis. In a typical scenario, we always set a threshold to filter the top ranked differentially expressed genes and...

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Bibliographic Details
Main Authors: Tinghua Huang, Siqi Niu, Fanghong Zhang, Binyu Wang, Jianwu Wang, Guoping Liu, Min Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Genetics
Subjects:
transcription factor
transcriptome data
correlation analysis
Kendall’s tau
Jinzer
Flaver
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1511456/full
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